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Shiseido Partners With RepliCel to Launch Hair Loss ‘Cure’ in 2018

2018According to Yahoo! Japan, the Japanese skincare and cosmetics company Shiseido has announced that its hair loss ‘cure’ should be ready to be made commercially available in 2018.

Shiseido has partnered with RepliCel Life Sciences on a ‘hair regeneration’ project which involves replicating follicles to combat both Male and Female Pattern Hair Loss and promote healthy regrowth. Although RepliCel previously announced the product could be ready as early as 2016, it appears the launch has now been delayed.

Pluripotent stem cells

Shinya YamanakaWe previously reported on the RepliCel method, which draws on the findings of Japanese scientist, Shinya Yamanaka (pictured), who won the 2012 Nobel Prize for Physiology or Medicine after discovering that mature cells can be converted into stem cells.

Whilst this ground-breaking cell regeneration development is being used to create ‘cell pharmaceuticals’ – which can help repair nerve damage – using the information to treat thinning hair is reportedly seen as the real ‘cash cow’ of regenerative medicine.

His pluripotent stem cell findings were recently furthered in specific relation to genetic hair loss by a team at the Sanford-Burnham Medical Research Institute in California. They found that human stem cells could be converted to dermal papilla cells, using the pluripotent stem cells. As dermal papilla cells are an integral part of the hair follicle formation and hair growth cycle processes, the study concluded that, following successfully regrowing hair in mice during trials, their method for inducing hair growth could also work on humans.

About the RepliCel process

In order to fully understand how the concept behind Shiseido and RepliCel’s method for restoring hair would work, it is necessary to first know what causes androgenetic alopecia.

Testosterone byproduct, DHT is found in the bloodstream of both men and women. In those with a genetic predisposition to hereditary hair loss, DHT attacks hair located around the top of the scalp by binding itself to the hair follicles. This on-going DHT onslaught gradually weakens the targeted follicles – a process technically known as ‘miniaturisation’. This causes the hair to thin and can potentially even lead to baldness which is where the hair follicle dies completely.

Shiseido and RepliCel’s technique revolves around re-activating the existing hair follicles. In order to do this, hairs are extracted from the scalp at root level – making it less invasive than a hair transplant – and specific cell populations are isolated from the person’s own healthy hair follicles. These cells are then replicated into the millions and injected back into affected areas of the scalp.

What is not immediately clear is how this procedure could be sold to the public; we assume it is likely to be delivered in the same format as some of Shiseido’s beauty treatments, so could perhaps take place in spa-type environments, as well as at dermatology and hair loss clinics.

Though it is unlikely to be suitable for home-use, we did find information from RepliCel which notes they are ‘also developing a propriety injection device optimised for the administration of its products and licensable for use with other dermatology applications’. We will report any new updates on these delivery systems, as soon as information becomes available.

Timeline for launch

According to a press release issued by RepliCel, Shiseido has an exclusive license for the hair loss product known as ‘RCH-01’ in certain Asian countries including Japan, China and South Korea. There is no mention yet as to when it will launch – although they expect it to be in 2018 – and whether it will be made available outside of these territories, through Shiseido or any other brand.

The product is currently undergoing ‘multiple clinical trials’ which will continue throughout 2015. Additionally, Shiseido is carrying out its own clinical trial ‘of RCH-01 and the device’ which has no date attached but is said to be scheduled to happen ‘in late prototype development’.

Where genetic hair loss is concerned, three years can be a long time. If you are concerned that you are losing more hair than usual and would like to investigate ways to prevent further shedding and regrow your hair, visit a hair loss specialist sooner rather than later. They can provide you with a diagnosis of your condition then tailor a personalised hair loss treatment plan featuring clinically-proven components which, if followed as directed, should start to produce visible regrowth results within the first three to six months.

The Belgravia Centre Hair Loss Clinic - Hair Loss Specialist ConsultationThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.

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15th February, 2016 at 12:28 pm

Scott Waterhouse

Credit to Japan. Not just in this treatment but their relaxation of stem cell tests and usage. This will mean everything from skin regeneration to hair regeneration within the next 10 years or so will come out of Japan.

26th April, 2016 at 7:14 pm


Hi please help me I think I may be losing some of my hair is this seirous ?could I die ? what should I do have you any good helpful advice

27th April, 2016 at 10:50 am

Sarah Belgravia

Hi Claire, Chances are your hair loss is nothing serious - the great majority of hair loss conditions only affect the hair and have no other affects on your health - so do try not to worry. Sometimes excessive hair fall is temporary and will clear up on its own in a few months time, whilst in many other cases it may be a permanent condition but clinically-proven treatment may help to prevent further shedding and promote regrowth. The best thing to do to put your mind at rest is to have a professional hair loss consultation. You can either make an appointment for a free consultation in person at one of our Central London clinics or if you are unable to visit us due to your location, you can complete an online consultation.

21st May, 2016 at 7:11 pm

Manish Kumar

Hello sir, I am loosing my hair very fast and I want a payment solution for this.if you launch this product in India It will bring happiness for millions of Indian who suffer hair loss. Kindly launch as soon as possible.

4th July, 2016 at 5:27 am

James Frank

Is there any information as to how much this will cost?

4th July, 2016 at 11:11 am

Sarah Belgravia

Hi James, No, sorry - until the clinical trials are finished and the product's safety and efficacy assured, pricing information will not generally be made available.

16th August, 2016 at 5:05 pm

Jay Daoust

It will certainly cost a lot less than traditional FUE techniques. If you have already been through surgery such as I have and still need more graphs because of naturally thin hair, the cost comparison will not phase you in the least. If I were to take a conservative guess, I would say, this treatment would be available in special clinics or spas etc. for minimum $1000 per treatment. At least until clinics become competitive.

18th August, 2016 at 2:54 am

Mir piral khan talpur

hi my hair is 50% Loss so plzz treatment my hair

18th August, 2016 at 4:15 pm

Sarah Belgravia

Hi Mir, you can find out about this on our hair loss treatment page or, if you would like personalised recommendations, please arrange a free consultation at one of our Central London hair loss clinics. Alternatively, if you are based outside London or the UK, you can complete an Online Consultation instead.

6th September, 2016 at 12:03 pm


Hi Team, Can you let us know the status of the clinical trails and how effective are they proving out to be. I hope that this treatment is out atlest by this year or early 2017. What does the probability look like ? Thanks.

6th September, 2016 at 12:45 pm

Sarah Belgravia

Hi Anup, there is little hope of this treatment being available before 2018 although as the estimated release date keeps getting pushed back, 2020 may be a better estimate.

14th September, 2016 at 12:29 am

Pedro maldonado

Is it true?? Es esto verdad o es otra de los "buscones de dinero??,

14th September, 2016 at 10:23 am

Sarah Belgravia

Hi Pedro, the information provided is correct. Whether or not the product will pass the necessary efficacy and safety tests to bring it to market is as yet unconfirmed so we cannot comment on whether it will work or not at the moment.

3rd October, 2016 at 7:26 pm


I'm offering my scalp for you guys in Japan to test out your new product so hurry up and get in touch I can get on plane immediately!

4th October, 2016 at 2:25 pm

Sarah Belgravia

Hi Jonny, you'd need to contact the companies involved directly I'm afraid - we are not involved in these trials.

6th October, 2016 at 7:16 pm

Darren Bouchard

Hurry it up.

8th October, 2016 at 7:53 am

Wise Owl

Ever since I was 14 years old I noticed I was losing my hair. My older brother was the same and he went through lots of treatments from topical to surgery and I am glad that I have not done anything yet. He treatments have not worked and he has spent thousands and thousands of £'s. Eventually a breakthrough in true hair restoration will come through. However we just need to be patient and not jump onto anything that comes out. A lot of people find it very hard to deal with hair loss because we live in a world where "image" is presented as really important. However I look at what I have that I should be grateful for i.e. good health, family, freedom to travel. We are living in an age where technologies are advancing very quickly and I do believe that a breakthrough in hair restoration will be coming within the next 10 years. All the best everyone.

16th October, 2016 at 10:34 am


Is the trials still going on or is this another one of them things iv read about and never to be hear about again..nice to think there will be soothing in the next couple of years sick of been bald..can you let me no thanks

17th October, 2016 at 9:47 am

Sarah Belgravia

Hi Martin, these trials are happening right now. You can check out our blog for updates.

17th October, 2016 at 9:33 pm


Hi Fam, so i am getting older now..2 years ago i lost my partner in a car accident and now i have just got back into the dating scene, i am having trouble finding an attractive partner due to my hair loss. i am 28 years of age.. and have lost most of my frontal hair i have recently noticed a bald patch starting to appear at the top of my head. should i get a hair transplant or go for the completely bald shaved look? i dont think i can pull it off though. i am physically fit and work in an office where stress is potentially the main cause of hair loss. should i resign and live on a resort island? Help please

18th October, 2016 at 9:39 am

Sarah Belgravia

Hi Ossy, it sounds like you have been through a stressful time but there's no need to move to an island on account of your hair! A receding hairline and thinning crown are classic signs of male pattern baldness. The cause of this is genetics - it is an inherited condition - although you are right that stress can make this type of hair loss worse. Try to manage your stress through exercise and/or relaxation techniques.

You can of course try shaving your head - many men like this look but it boils down to whether it suits you and you feel confident with it. If you would prefer to try to keep and regrow your hair, we offer effective non-surgical solutions. These hair loss treatment courses are personalised to each individual's specific needs and feature clinically-proven medication as well as hair growth boosters. You can find out more about Belgravia's treatment courses, the types of regrowth results they can produce and how to arrange a consultation with our specialists here on our website.

23rd October, 2016 at 7:39 pm


Sarah Belgravia ...plz let me tel im totally bald if i use the product in 2018 when ever it is available can i get my thick hair back ..

24th October, 2016 at 10:23 am

Sarah Belgravia

Hi Fransis, it is unlikely this will reverse complete baldness as it involves stimulating hair follicles. When the scalp takes on a smooth, shiny appearance and complete hair loss, it means the hair follicles have died and, therefore, there is nothing left to stimulate.

25th October, 2016 at 9:32 am


Need to be prove

28th October, 2016 at 10:26 am


Sarah Belgravia alteast by next year that means by 2018 it wil be available in market??

28th October, 2016 at 1:19 pm

Sarah Belgravia

Yes, Fransis - the latest estimated date is 2018, however this date has been pushed back by the researchers a number of times already so we wouldn't be surprised to see this delayed until at least 2020. We will report on any updates or release dates on our hair loss blog so keep checking back for the latest information. If you are worried about thinning hair or a receding hairline now though, it is better to seek at least professional advice so you can find out sooner rather than later about the effective, clinically-proven hair loss treatment options already available.

31st October, 2016 at 2:22 pm


Hi.... I had severe breakage and severe hairfall after a chemical relaxant. I have fine Indian hair. Yes i was dumb. I can see my scalp. Patches have fallen off. It's been 4 and a half months and i have a slight improvement. I used minoxidil for 3 months. Was doing well on it but after a while my scalp could not tolerate it. Now that I have stopped the minoxidil I am shedding... what can i do... help help help

31st October, 2016 at 8:14 pm

John Satino

I have been studying hair loss & pluripotent stem cells since 2008 , This is the correct direction to go. the genetic stable hair is an organ, and can be duplicated, However after one or two generations the cells loose their memory and do not become a hair follicle, this has to be overcome to get multiples from these cells.

4th November, 2016 at 3:14 pm

Sarah Belgravia

Hi Yasmin, I hope the information contained in this response is helpful to you.

15th November, 2016 at 10:24 pm


When the scalp takes on a smooth, shiny appearance and complete hair loss, it means the hair follicles have died and, therefore, there is nothing left to stimulate. Is this true ? Cause i honestly tried every product out there , this stem cell thing gave me hope .I am bald ,shall i give up hoping ?

16th November, 2016 at 10:40 am

Sarah Belgravia

Hi Mark, the current medically-proven hair loss treatments are able to work in many cases of male pattern baldness. If the scalp becomes shiny and is truly bald, it is true that these cannot work, however some treatments - which are unlikely to arrive for many years yet due to being in the early stages of testing - are being developed that researchers hope will also work on true baldness. I hope that clarifies everything for you.

3rd January, 2017 at 1:52 am


Every year someone comes out with an on the "horizon" cure. From following such posts for many years I have come to the conclusion that 2050 seems a good chance.

3rd January, 2017 at 3:52 am


Who can I contact for trials ? And can this please hurry up balding doesn't stop I'm 22 and going bald really bald. Waking up drepressed and having sleepless nights over hair loss because there's nothing that works.HURRY !!b

5th January, 2017 at 4:47 pm

Saurav sharma

Hi sarah..i am a 16 yrs old and have been losing hair for past 1 year..my scalp skin also shed a lot..my hair loss is not stopping..i had vitamin tablets, folligan lotion etc..but my hair loss has not even stopped a bit..plz help

13th January, 2017 at 2:42 pm

Sarah Belgravia

Hi Sam, you would need to contact Shiseido or RepliCel directly as we are not involved in these trials. However, there are already effective male hair loss treatment options available now so it is probably worth your time looking into these first.

10th March, 2017 at 12:41 pm

Sarah Belgravia

Hi Saurav, we cannot diagnose you from what you say here so we recommend you have a personal consultation either at one of our hair loss clinics or online if you are unable to make it to London

1st August, 2017 at 3:16 pm

Steven pasha

Hi i had a transplant six years ago harley street , but its not the greatest would having another affect the transplanted hairs i jave already im 50 I had 5000 fue but very weak and wispy ps i have very strong hair back and sides

1st August, 2017 at 5:01 pm

Sarah Belgravia

Hi Steven, we don't actually offer surgical hair restoration procedures, all our results are achieved using medications - oral, topical or (most commonly) both - plus a range of hair growth boosters. One of our specialists can assess you and give you personalised advice and custom hair loss treatment recommendations if you would like? If you are based in London, please call us on 020 7730 6666 otherwise you can use our online form for a free consultation. I hope this is helpful.

7th October, 2017 at 10:01 pm

Arnold Jasvarich

If someone has already had a FUE transplant done in the past, can the ointment/treatment you are studying and plan to release still be used.

14th October, 2017 at 9:34 am

yusuf sheikh

Hi I am from india I have lost my 75 percent hair.i am 35 year old , I would like to new hair regrowth.how long will wait for replicel.

16th October, 2017 at 9:27 am

Sarah Belgravia

Hi Yusuf, there is no further news on RepliCel, suggesting the potential launch date may have been pushed back again. Medications and treatments can only be brought to market once they have passed rigorous safety and efficacy testing. This cannot be rushed and that is the stage that RepliCel was in the last time an update was circulated. As soon as we hear more, we will report the details on our blog.

16th October, 2017 at 9:41 am

Sarah Belgravia

Hi Arnold, this drug is the work of Shiseido and RepliCel - The Belgravia Centre is not involved in these trials or the development - so you would need to address your query to them. Best of luck!

29th October, 2017 at 8:12 pm


These are all empty promises. 15 years ago, than 10 years ago they (I mean the industry) said exactly the same - in 3-5 years we will have the solution. Now they are saying 2018. I can bet that no treatment like this will be available in 2018. May be in 15-20 time. Of course they will keep publishing those articles, and of course the research is ongoing, BUT.... no real good treatment in next 15 years. Absolutely sure about this.

31st October, 2017 at 2:09 pm

Sarah Belgravia

Hi Mike, we fully understand your skepticism and in many cases the dates for treatments do get pushed back. It is something of an industry 'joke' that there is always a 'cure' said to be five years away. However, current developments in certain areas - namely JAK inhibition and stem cell hair replication - are advancing apace, and also have big, committed pharmaceutical companies with big money behind them in many instances. Those which currently look to be the most promising - RepliCel and the portfolio of JAK inhibitors developed by Columbia University and licensed exclusively to Aclaris Therapeutics - have showed continuous progress over the past few years and have produced a stream of updates during this time - something many trials fail to do and these tend to be the ones which disappear. We believe that, if development progresses at its current rate and everything meets the necessary MHRA and FDA critera for safety and efficacy, by 2020/2021 there will be significant developments in the options available for hair loss treatments. Most excitingly of all, these should include the first viable treatment options for people who are totally bald due to the severe autoimmune disorders Alopecia Totalis and Alopecia Universalis.

2nd January, 2018 at 9:33 pm


when the cure will be available? thanks

3rd January, 2018 at 11:20 am

Sarah Belgravia

Hi John, a release date has not been announced. Often these dates are estimated and based upon no delays in the research, trials and approvals process - which is rarely the case. As soon as more information on this treatment becomes available, we will publish it on our hair loss blog.

10th January, 2018 at 8:42 am

ChuanWei Chiang

Will you create the therpy center in Taiwan or China if RCH01 are available?

10th January, 2018 at 1:20 pm

Sarah Belgravia

Hi ChuanWei, no we do not offer this treatment - we only offer clinically-proven and MHRA/FDA approved hair loss solutions - and have no plans to open clinics outside of the UK. However, we are able to send our hair loss treatment products to Taiwan and China. If this is of interest, please complete our online consultation form and one of our team will be with you shortly to provide a diagnosis and treatment recommendations personalised to your needs.

11th January, 2018 at 2:40 am

ChuanWei Chiang

According to Yahoo! Japan, the Japanese skincare and cosmetics company Shiseido has announced that its hair loss ‘cure’ should be ready to be made commercially available in 2018.That is an announcement I saw. Will RECH01 be a solution or tretment.

11th January, 2018 at 10:57 am

Sarah Belgravia

Hi ChuanWei, that is the information above, however, this was announced quite a while ago now and no updates have been made since then. The drug is still not MHRA or FDA cleared so it is unlikely to still be on schedule, which often happens.

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