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Belgravia Centre Hair Loss Treatment Before and After Results - New Success Story

alert male pattern hair loss the belgravia centre 17 04 2018A new entry has just been added to Belgravia’s Male Hair Loss Treatment Success Stories gallery.

Mr B, pictured, has seen an improved general density since he started his Belgravia treatment course.

Find out what he had to say and see his regrowth results close up, or find out more about treating Male Pattern Baldness by clicking the buttons below…

(Results may vary and are not guaranteed)

 

VIEW SUCCESS STORY

TreatmenT information 

 


Belgravia Centre Hair Loss Clinic Hair Loss Specialist Free ConsultationThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


HairlossANSWERS - Click to Submit Your Query to Our Hair Loss Experts

Name: Jools

Question: Can CBD oil treat hair loss? I have thinning hair and heard this is good for regrowth.

Answer: Hi, Jools. You haven’t mentioned the cause of your hair loss but, regardless, there is no clinical evidence that suggests CBD oil can treat thinning hair.

Cannabiniol oil – also known as cannabis oil and CBD oil – comes in a range of strengths and strains, depending on the type of hemp leaves it is produced from.

CBD oil cannabidiol cannabis oil hemp oilThere are around 113 active chemicals in the cannabis sativa plant, known as cannabinoids. The two key components are tetrahydrocannabinol (THC) and cannabidiol (CBD). Whilst THC is the banned psychoactive known for getting people high, CBD is considered an anti-psychotic and makes up approximately 40 per cent of cannabis extracts.

Hemp and marijuana are both cannabis sativa plants, but differ in that hemp plants tend to be farmed for their non-psychoactive CBD benefits, whilst marijuana plants have often been modified to ensure high levels of THC.

Studies are still underway but CBD has already been found to be beneficial to a range of health problems including epilepsy, Alzheimer’s disease, anxiety and inflammation. Furthermore, it has a low side-effect profile, being largely well-tolerated with the main complaint in users being tiredness.  In August 2016 it was reported in The Independent that the NHS is developing a CBD vape pen, known as the MediPen vaporiser, to help people deal with a range of health issues. Despite this, it is not presently MHRA licensed, nor FDA approved for the treatment of any condition.

Cannabiniol use for medical purposes is legal in many countries, including Australia, Canada, Denmark, Greece, Italy and Germany, whilst in America the law varies by state to state. Though cannabis use is illegal in the UK, carrying potential penalties for possession of up to 5 years in prison, an unlimited fine or both, the use of CBD is legal.

In some cases the NHS is actually able to prescribe CBD, commonly referred to as medical marijuana, though this is generally for pain management when other options have been exhausted, and not for issues considered to be ‘cosmetic’ and where its effects are unproven, such as hairloss.

Hair Vitalics Belgravia Centre Hair Growth Supplement Men WomenOne reason CBD oil appears to have been widely touted on the internet as a potential hair loss solution, is due to its nutritional properties. It is rich in the fatty acids omega 3 and omega 6 – something researchers at the University of Seville found to be present in the ‘1/4 ratio’ considered optimal for health. It is also understood to contain good levels of linoleic and gamma linoleic acid (GLA) – essential fatty acids which promote the maintenance of normal hair growth – as well as calcium, phosphorus, magnesium and potassium. Additionally, cannabiniol oil is said to be high in vitamin E.

As such, it may help to improve the condition of the hair in the same way following a balanced, healthy diet would. However, CBD oil is highly unlikely to treat a medical hair loss condition, especially if this is a genetic complaint – namely Male Pattern Baldness or Female Pattern Hair Loss, both of which cause thinning hair anywhere in the vertex area from the crown to the hairline, in those affected.

Despite it usually being taken orally, we are aware of CBD oil being used as a topical treatment for scalp conditions such as eczema and seborrhoeic dermatitis, though the evidence to support this type of therapy is currently solely anecdotal.

Discovering an effective, natural treatment or cure for hair loss would be fantastic but, to date, there are none that have been proven to work in regrowing hair or preventing baldness. There are, however, clinically-proven pharmaceutical hair loss treatments available, which – at Belgravia – are offered alongside additional supporting products and therapies tailored towards maximising hair growth and condition.

These include FDA-cleared low-level laser therapy (LLLT) devices, such as the LaserBand products, and premium Hair Vitalics food supplements, in highly-targeted Men’s and Women’s formulations, comprising a range of beneficial vitamins, minerals, amino acids and botanical extracts including selenium, zinc and biotin to promote normal, healthy hair growth.

The first step we would recommend you take, however, is to establish the precise reason your hair is thinning. There are a number of reasons that this can happen and a professional diagnosis is usually the best way to ensure you know exactly what is happening, why and how to address it.


The Belgravia Centre Hair Loss Clinic - Hair Loss Specialist ConsultationThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


Related Stories


Many men worry about going bald but, if you knew you were likely to lose your hair, how far would you go in the hope of preventing baldness?

Would you, for instance, have strong, healthy hairs extracted now and cryogenically frozen until you decided to have the relevant cells injected back into the areas affected by Male Pattern Baldness?

This may sound rather far-fetched and akin to science fiction but, thanks to an innovative new hair loss solution being developed by start-up company HairClone, this could actually be science future.

The Anatomy of a Hair FollicleThe future of hair loss prevention?

Various organisations have already published findings from their hair follicle cloning research, an area that has been pushing medical boundaries over the past 40 years.

These include the Canadian company, RepliCel which is developing stem cell replication techniques to treat Male and Female Pattern Hair Loss, and the Keck School of Medicine at the University of Southern California. There, a team has created a technique which allows them to grow functioning hair follicles directly from skin stem cells, in a lab, ready to be implanted into patients. This could potentially provide a method of treating not only genetic hair loss, but also currently untreatable hairloss conditons, such as those caused by scarring.

Taking its lead from such ground-breaking innovations, HairClone has assembled a team of scientists and clinicians – including top surgeon Dr Bessam Farjo dedicated to increasing the efficacy of hair cloning methods, with a view to bringing them into general practice.

The British business is refining an interesting proposition whereby men concerned about going bald could take preventative steps via a straightforward 30 minute procedure.

This entails having around 50 follicular units harvested under local anaesthetic using a small punch device. This part of the process is the same as current hair transplant methods, and the extraction is performed using Follicular Unit Extraction – recently renamed Follicular Unit Excision – more commonly referred to in both instances as FUE.

Traditional hair restoration surgery would then involve grafting each donor hair follicle straight back into the patient’s scalp, wherever needed – to fill in a receding hairline or thinning crown, for example.

Where HairClone differs is in that, once hair units have been extracted, the patient is free to go home straight away. This is because the donor hair follicles are taken years in advance of hair loss occurring – or at least it becoming sufficiently problematic as to warrant immediate action. They are then cryogenically preserved until the patient needs them so that, by the time signs of hair loss become evident, they have already ensured follicles of a suitable quality are available to address the issue.

HairCloneCryogenic hair follicle bank

This type of follicle banking could provide a unique service to people concerned about losing their hair. The business’s aim is for HairClone clients to store ‘a small number’ of follicles in the cryogenic facility, which will then keep them at a temperature f -197C until needed.

The hair follicles can be cryopreserved for ‘many years’, according to the company’s website, which explains the process when the patient decides to use them, as follows:

‘…some of the follicular units would be taken from the bank and processed to isolate the specific cells involved in the production of the hair shaft itself. These cells would be grown in culture in MHRA licensed laboratories and they would divide and multiply rapidly over 2-3 weeks. These expanded cells would then be transported back to the clinic and micro-injected into the patient’s scalp where needed where they would be expected to rejuvenate the thinning vellus hairs causing them to produce thicker terminal hair shafts and regain a more youthful appearance. In a later version of the product injected cells would be able to create brand new hair follicles by a process called follicle neogenesis.’

The ‘specific cells’ isolated via donor follicle micro-dissection are – or at least include, HairClone does not specify – Dermal Papilla (DP) cells. These are found at the base of hair follicles and determine how thick hairs will be. Hairs are then produced by the dermal sheath cells. As researchers from the University of Durham explain in the Lancet, ‘The dermal sheath that surrounds the outside of the hair follicle contains progenitor cells that maintain and regenerate the dermal papilla, a key component for hair growth.’

Scientists at the University of Calgary discovered follicles in bald skin contain dysfunctional DP cells, and dermal sheath cells may have the ability to self-renew. This indicates a role not just in hair thickness, but also in the hair growth cycle.

HairClone’s service is still in development and has established three key areas which require further exploration before it could potentially become a mainstream hair loss treatment offering within the next three years. These are: finding how best to measure ‘hair follicle inductivity’ (the potential levels of efficacy) and to expand cells once in culture in order to maintain these levels, as well as determining precisely how the cells ‘rejuvenate and regenerate’ hair follicles once re-implanted into the scalp.

Hair loss solutions

There are already two well-established, clinically-proven male pattern hair loss treatment drugs which are both MHRA-licensed and FDA approved – one topical solution and one oral tablet. Clients at Belgravia are offered custom treatment solutions, tailored to their precise pattern and level of shedding, and tend to feature appropriate formulas of key medications alongside supporting products and therapies designed to encourage healthy hair growth. 

Though these are widely-used to stabilise hair fall, help regrow hair and prevent baldness, this new approach could come in handy as a potential backup for well-organised, forward-thinkers.

For instance, in some cases a man may not decide he wants to do something about his receding until it has reached an advanced point where the follicles are no longer capable of responding to pharmaceutical treatments. In this case he may decide to explore hair transplant surgery. However, as HairClone advise, ‘There is an increasing amount of scientific evidence that would indicate that hair cells and hair transplant quality decreases with age. Therefore, harvesting and banking hair cells at an early age will be expected to preserve high cell potency for future uses‘.

Clinical testing and follicle banking has already started but estimates as to when the procedure may be ready to obtain necessary approvals from medical regulatory boards in order, vary. Given that Male Pattern Baldness is a permanent condition which causes on-going follicular miniaturisation in the affected areas from the hairline to the crown, those with thinning hair now may find it’s not feasible to wait at least another three years.

Whilst HairClone is certainly an exciting proposition, anyone concerned about going bald now should start to explore their options as early as possible.


The Belgravia Centre Hair Loss ClinicThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


Related Stories


Belgravia Centre Hair Loss Treatment Before and After Results - New Success Story

alert male pattern hair loss the belgravia 16 04 2018A new entry has just been added to Belgravia’s Male Hair Loss Treatment Success Stories gallery.

Mr T, pictured, has maintained his results after an initial period of regrowth when he started treatment three years ago.

Find out what he had to say and see his regrowth results close up, or find out more about treating Male Pattern Baldness by clicking the buttons below…

(Results may vary and are not guaranteed)

 

VIEW SUCCESS STORY

TreatmenT information 

 


Belgravia Centre Hair Loss Clinic Hair Loss Specialist Free ConsultationThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


Belgravia Centre Hair Loss Treatment Before and After Results - New Success Story

alert male pattern hair loss the belgravia centre 13 04 2018A new entry has just been added to Belgravia’s Male Hair Loss Treatment Success Stories gallery.

Mr J, pictured, is thrilled with the results of his treatment to date saying “the treatment started working almost immediately.”

Find out what else he had to say and see his regrowth results close up, or find out more about treating Male Pattern Baldness by clicking the buttons below…

(Results may vary and are not guaranteed)

 

VIEW SUCCESS STORY

TreatmenT information 

 


Belgravia Centre Hair Loss Clinic Hair Loss Specialist Free ConsultationThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


When it comes to the divisive American President Donald Trump, it seems there’s one truth that’s universally acknowledged: the man has strange hair.

After revelations that his daughter, Ivanka, jokes to friends about how her father achieves his unique hair colour and style following the flap surgery he is said to have undergone in an attempt to curb his hair loss, the controversial POTUS has largely remained uncharacteristically quiet.

To date he has simply maintained that his hair is his own – often inviting people to touch it at rallies. However, at the February 2018 Conservative Political Action Conference in Maryland, the 71 year old admitted he tries “like hell” to hide his Male Pattern Baldness.

“I work hard at it”

CNN footage – which can be seen below – shows the President catching a glimpse of himself on a big screen at the event, then going off script and telling the crowd about his hairloss.

By the way, what a nice picture that is,” Trump told the GOP supporters, motioning to his own image. “Look at that. I’d love to watch that guy speak.”

Oh, I try like hell to hide that bald spot, folks,” the infamously coiffed Republican admitted, referring to his thinning crown.

I work hard at it. It doesn’t look bad,” he opined before coming to the confusing, tangenital conclusion: “Hey, we are hanging in, we are hanging in, we are hanging in there. Together, we are hanging in.”

Whether the ‘we’ in question refers to Donald Trump and his thinning hair, or President 45 and his supporters was unclear.

Regrowing hair on a thinning crown

Though Donald Trump’s hair loss is arguably a lost cause given his age and the extent of the shedding – Ivanka is said to have referred to his scalp under the carefully constructed hairstyle as a ‘completely bald pate’ – there are clinically-proven medications available to treat a thinning crown. When the hair follicles are still active, even if they are producing thin hairs, these MHRA-licensed and FDA approved drugs can be a viable option for men looking to stabilise hair fall, promote regrowth and prevent baldness without resorting to surgery.

The Donald’s personal physician, Harold Bornstein, told the New York Times his patient uses one of these – a one-a-day tablet designed to inhibit the formation of dihydrotestosterone (DHT), the hormone which causes hair thinning in genetically predisposed individuals – though how effective this is for him is unknown. It may simply help the former TV presenter to hang on to the hair has by reducing the amount of DHT in his bloodstream. The other, topical, medication is not suitable for men of the President’s age.

At Belgravia specialists tailor customised hair loss treatment courses to the individual needs of each client, including their age, medical profile, pattern and level of shedding. Their course will not only include appropriate key medications but also additional hair growth supporting products and on-going monitoring by a dedicated team who are available to answer any queries and provide personal assistance during the process.

This is a confidential service, but anyone wishing to follow Trump’s lead and talk publicly about their hair loss issues is, of course, very welcome to do so.


Circ - Male Pattern Baldness hair loss treatment Belgravia Centre clinic LondonThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


Related Stories


Belgravia Centre Hair Loss Treatment Before and After Results - New Success Story

alert male pattern hair loss the belgravia centre 11 04 2018A new entry has just been added to Belgravia’s Male Hair Loss Treatment Success Stories gallery.

Mr B, pictured, has seen lots of new growth in the areas affected by his hereditary condition.

Find out what he had to say and see his regrowth results close up, or find out more about treating Male Pattern Baldness by clicking the buttons below…

(Results may vary and are not guaranteed)

 

VIEW SUCCESS STORY

TreatmenT information 

 


Belgravia Centre Hair Loss Clinic Hair Loss Specialist Free ConsultationThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


HairlossANSWERS - Click to Submit Your Query to Our Hair Loss Experts

Name: Ali

Question: I’ve heard that mesotherapy hair loss treatment can be good for thinning hair – can you tell me what it involves and does mesotherapy work well for regrowing hair?

Injection Syringe Vaccination MedicalAnswer: Hi, Ali. Mesotherapy for hair loss is a popular topic at the moment thanks to the technique becoming more widely available, though there appears to be little evidence regarding the scalp injections’ supposed benefits.

The practice was initially used in 1976 to treat asthma and hearing loss but has since been co-opted into ‘treating’ a number of other issues. It has not been sanctioned in any way, for the treatment of any condition, by the UK or USA’s medical regulatory boards the MHRA and FDA. The American Center for Disease Control and Prevention (the CDC) has recommended: “providers should adhere to recommend standard precautions, follow safe-injection practices with appropriate aseptic techniques, and inject only FDA approved products that are prepared following guidelines to ensure sterility as described in the FDA’s good manufacturing practices.”*

Going by a number of names – including biomimetic mesotherapy and nanopeptide mesotherapy – this cosmetic procedure involves a solution, usually featuring ingredients thought to boost blood circulation, being injected into various locations in the scalp. Ingredients used in this mixture tend to include vitamins such as biotin, amino acids and growth factors though the precise components depend on the brand and practitioner.

The aims of this are widely stated as being promoting hair growth, treating hairloss in cases of thinning, and preventing baldness – though we are unaware of mesotherapy being recommended in cases of autoimmune disorders such as alopecia areata.

Generally it is used on men and women with androgenetic alopecia – more commonly known as male pattern baldness and female pattern hair loss. These hereditary conditions cause thinning hair in the area of the scalp affected by follicular miniaturisation caused by a genetic sensitivity to dihydrotestosterone (DHT). This is the vertex area from the hairline to the crown, inclusive.

In men, hair thinning locations tend to be more well defined – for instance, they may develop a receding hairline or a thinning crown. Conversely, women’s hairloss tends to be more diffuse, causing shedding all along the top of the scalp, frequently noted by an increasing widening of the parting. The reason this is important is that mesotherapy involves scalp injections in the affected areas. So, the larger these are, the more injections will be required and, in some cases at least, the more you will pay.

Hair Vitalics Belgravia Centre Hair Growth Supplement Women MenAlthough it is a quick day-patient procedure, taking around half an hour to perform each session, after-effects can include bruising, swelling and itching. Speaking to the Daily Mail, Conservative politician and TV personality Nadine Dorries admitted applying a hot water bottle to her head after undergoing nanopeptide mesotherapy for her hair thinning.

The most recent clinical trial information regarding this elective procedure comes from the University of Egypt, whose December 2017 study was published in the respected Journal of Cosmetic Dermatology. The findings showed there were associated ‘late onset’ side effects of mesotherapy for alopecia – including scarring and, ironically, hair loss.

When it comes to thinning hair caused by male and female pattern baldness, there are already two MHRA licensed and FDA approved hair loss treatments. One, for men aged 18 or over only, comes as an oral tablet, and one unisex option, a topical solution which is applied directly to the scalp. At Belgravia, patients are offered tailored courses using the most appropriate components their dedicated specialists recommend, based on their pattern and level of shedding, as well as their medical profile. This may include non-medicinal hair growth supporting products being used alongside established drugs.

Two of these – Hair Vitalics for Men and Hair Vitalics for Women – are premium food supplements which contain a number of highly-targeted vitamins, minerals, botanical extracts and amino acids, including selenium, biotin and zinc to promote healthy hair growth.

Mesotherapy is not a clinically-proven hair loss treatment and it is hard for us to comment on its efficacy given the lack of credible data available and the fact that, due to this, it is not a service Belgravia provides. Of the medical studies that have been carried out, the general consensus is that it is a ‘controversial practice’** for which ‘proper regulation’*** is needed. Given a quick Google search of UK mesotherapy practitioners returns a number of entries claiming – highly dubiously given the natural timeline of the hair growth cycle – that results can be seen in as little as two days, we would certainly agree with these statements.

* Source: American Society for Dermatologic Surgery; Mesotherapy and phosphatidylcholine injections: historical clarification and review – DOI: 10.1111/j.1524-4725.2006.32100.x
** Source: International Journal of Trichology; Mesotherapy in the Management of Hair Loss – DOI:  10.4103/0974-7753.66914
*** Source: Journal of Cosmetic Dermatology; Hair Loss at Injection Sites of Mesotherapy for Alopecia – DOI: 10.1111/jocd.12320

 


The Belgravia Centre Hair Loss Clinic - Hair Loss Specialist ConsultationThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


Related Stories


Researchers from the Francis Crick Institute in London and the University of Dundee have made a key scientific breakthrough which may have beneficial implications for hair loss and hair growth.

They examined the role of a protein called PAWS1 in the Wnt signalling pathways; these pathways pass signals into a cell which tell it how to function.

Because Wnt signalling pathways play such a vital role in bodily growth, mutations can often cause developmental defects and disease, ranging from cancer to hairloss. A study carried out by Stanford University in the US confirmed this notion, finding the Wnt signalling pathways to be critical for sustained hair growth.

Grant Hill, press officer at the University of Dundee, noted PAWS1 had the potential to address “potentially deleterious alterations to Wnt signalling”. This discovery may have key ramifications for hair loss treatments in the future.

PAWS1 breakthrough

Hill explained the researchers previously discovered PAWS1 is involved in a range of signalling processes involved in the development of bone, cartilage and other tissues in the human body”.

It is also crucial when shaping the development of embryos and determining the fate of cells in adults.

The Dundee-Crick team explored the molecular process through which PAWS1 controls Wnt signalling. This research was published in the EMBO Reports journal.

According to Hill, the research was conducted on frogs because “the activation of Wnt signalling in frog embryos is known to cause a two-headed tadpole”.

The findings revealed PAWS1 is a “crucial regulator” of the enzyme Caseine Kinase 1 alpha (CK1α) in Wnt signalling pathways.

PAWS1 mutations which were found to be incapable of effectively associating with the CK1α enzyme failed to produce two-headed tadpoles. They were also unable to activate Wnt signalling. Furthermore, when the team removed PAWS1 from a human osteosarcoma cell line (a malignant bone tumour), Wnt signalling was inhibited.

This suggests scientists may one day be able to correct alterations to Wnt signalling pathways in order to treat or prevent the diseases and conditions associated with it.

Hair growth implications

In a press release announcing the discovery, Professor Jim Smith of the Francis Crick Institute emphasises the protein’s role in hair growth: “Although the precise function of PAWS1 was poorly understood, PAWS1 mutations are known to cause palmoplantar hyperkeratosis, a disease in which there is excessive skin cell growth on the soles and palms and can affect normal hair growth leading to conditions such as alopecia”.

Smith continues “Wnt signalling is known to play crucial roles in the maintenance of skin tissue and hair development. Our findings… now offer an opportunity to establish whether the pathogenic PAWS1 mutations impact Wnt signalling to give rise to this disease”.

The hair loss condition to which Smith refers is unspecified – somewhat confusingly when the term ‘alopecia’ when used on its own simply means ‘hair loss’ without specificity. However, as other research in this area has tended to revolve around androgenetic alopecia – genetic hair loss, and particularly Male Pattern Baldness – this is likely to be the case here, though clarification has not been given.

Clinical trials are currently investigating a variety of stem cell based treatments for hereditary hair loss. A group of researchers funded by the US company Samumed has been trying to manipulate Wnt signalling pathways in the hope of encouraging new hair regrowth in cases of male pattern hairloss. RIKEN – a Japanese company – is also developing a cell regeneration method which would potentially allow artificial skin containing fully functioning hair follicles to be grafted into the scalps of people who are losing their hair from a number of conditions, including some which are currently untreatable, such as Cicatricial Alopecia.

While the work undertaken by the Dundee-Crick team reflects the huge potential presented by stem cell research in preventing baldness, this field is only just starting to be explored.

Given genetic hair loss is progressive, it is wise to address male and female pattern baldness sooner rather than later. Belgravia already treats these conditions, offering supportive, personalised treatment courses, which have produced many Success Stories to date. This approach provides on-going monitoring and uses clinically-proven, MHRA-licensed and FDA-approved medications which can be used alongside supplementary hair growth booster products as appropriate.


Belgravia Centre Hair Loss Clinic Hair Loss Specialist Free ConsultationThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


Related Stories


obesity weight loss diet health obese overweight healthy weight bmi waist measurementIn early April 2018 NHS Digital published a report by the Office of National Statistics into Obesity, Physical Activity and Diet in England.

The findings covered the period from 31st March 2016 to 31st December 2017 and showed that 26 per cent of adults in England are obese. Additionally, obesity-related National Health Service (NHS) hospital admissions rose by 18 per cent year-on-year to 617,000.

Subsequent implications for the nation’s health are far wider-ranging than simply waist measurements, however. One incidental issue arising from what is now known globally as the ‘obesity crisis’ is an increased propensity towards hair loss for those affected.

When does being overweight become obesity?

The NHS advises that whether or not a person is overweight or obese is currently measured using a Body Mass Index (BMI) healthy weight tool. Although this can be helpful in providing a guideline, it is not accurate for everyone as it does not take into account factors such as muscle mass and ethnicity.

The BMI calculator tool is considered more accurate for Caucasians than for other races when the defining weight range thresholds may be lower.

Measuring the waist circumference is also thought to be useful, and is a method used by GPs. ‘People with very large waists – generally, 94cm (37in) or more in men and 80cm (about 31.5in) or more in women – are more likely to develop obesity-related health problems,’ states the NHS website.

content provided by NHS Choices

 

The obesity crisis

The obesity crisis has been talked about for many years – and not just in the UK. However, this latest fact-finding mission relating specifically to England seems to have produced tangible evidence as to the current scale of the problem, and ways in which people are trying to combat it.

According to the NHS Digital statistics in 2016 there were 26 per cent of adults classified as obese – an increase of 15 per cent since 1993, though it has remained at a similar level for the past six years. Childhood obesity research indicated that one in ten reception-age children, and one in five year six children were obese.

Highlighting the health risks, the report states that there were 10,705 admissions to NHS hospitals in 2016/17 in which obesity was a primary factor, and 606,295 where it was a secondary diagnosis. Of these admissions, 66 per cent of patients were women.

The NHS explains: ‘Obesity reduces life expectancy by an average of 3 to 10 years, depending on how severe it is. It’s estimated that obesity and being overweight contribute to at least 1 in every 13 deaths in Europe.’

Does being obese cause hair loss?

Whilst being acutely overweight in itself is unlikely to cause hairloss, obesity can lead to an increased risk of developing many significant health issues -most of which are known to cause thinning hair. This can be either directly, or indirectly as a side-effect of medications used to treat these illnesses which include type 2 diabetes, coronary heart disease, liver disease, kidney disease, stroke, sleep apnoea and certain types of cancer, namely breast cancer and bowel cancer.

Therefore, an inference regarding increasing cases of hair loss and its links to obesity, backed by some of the key facts highlighted in the NHS Digital report – particularly those regarding hospital admissions and lifestyle issues such as diet and exercise –  is logical.

NHS Digital reports that in 2016 21 per cent of men and 25 per cent of women were classed as inactive, whilst only 24 per cent of men and 28 per cent of women consumed the recommended five portions of fruit and vegetables per day.

Nutritional deficiencies can cause diffuse hair thinning all over the scalp from a temporary condition called Telogen Effluvium. Although it can affect both sexes, it is most prevalent in women. Once triggered it can take around three months to present and often hair regrowth will resume naturally within six months, except in chronic cases when the shedding – which can affect approximately 50 per cent of the scalp – lasts for a minimum of six months but is still considered temporary.

Telogen Effluvium can, however, cause people with an existing genetic predisposition to hereditary hair loss – male and female pattern baldness – to see increased thinning. It can also kickstart the early onset of these conditions in cases where the were genetically predisposed byt had not yet presented. Where this does happen and it is a concern, people wanting to explore regrowing hair and preventing baldness can speak to a specialist about personalised hair loss treatment options as clinically-proven medications can help in many cases.

Exercise Biking Health FitnessObesity may also be a contributing factor in the current statistical trend for both men and women increasingly experiencing hair loss from a younger age than previous generations. One of the issues various experts have linked to a rise in premature male pattern baldness among young men is something called oxidative stress. This is related to lifestyle issues such as nutritionally unbalanced diets, regular excessive alcohol consumption and smoking.

Women have traditionally tended to lose their hair later in life than men, now though – seemingly thanks to the pressures of modern life – stress is thought to be the driver behind more cases of female pattern hair loss being seen in women in their 20’s.

Losing weight without losing hair

For people wanting to get to a healthy weight, it is important that their weight loss journey involves a sensible long-term plan in relation to both exercise and eating, rather than relying on any ‘quick fix’ solutions. Extreme dieting, crash or fad diets and over-exercising can all be problematic and cause thinning hair – again, due to Telogen Effluvium – from the strain they place on the body.

In some cases, where the body receives a real shock to the system after intense measures are taken, sudden bald patches from the autoimmune condition Alopecia Areata may be induced. This is what happened to ‘super slimmer’ Mandy Ballard who lost 17 stone in just two years by following a punishing exercise and restrictive diet regime after having a gastric sleeve fitted. In many cases hair regrowth will resume within 12 months of its own accord, though alopecia areata treatment may help to accelerate this process.

Taking a measured approach to making balanced dietary and lifestyle changes – with the help of relevant professionals where needed – is the best way to prevent hair loss from bodily stresses and strain. Among the many benefits of having healthy body and diet rich in a range of nutritional elements, this can help to support the normal functioning of both blood circulation and the hair growth cycle for strong, vital locks. Should any abnormal shedding occur, however, there is help and support available so should not detract from achieving any goals.


Circ - Belgravia Centre Hair Growth supplements boosters lasercombThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


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