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A press release from Italian-based Cassiopea, the pharmaceutical company developing a Clascoterone-based genetic hair loss treatment known as Breezula, has provided a “very positive” Phase IIa update.

This stage of the research was intended to establish the efficacy and safety of four separate doses of Breezula, and, according to its manufacturers, the topical anti-androgen has performed well, with no serious side effects related to the treatment being reported.

The press release, dated 16th April 2019, boldly claims the “results indicate that Clascoterone stops the loss of hair and grows new hair”.

What is Clascoterone (Breezula)?

Clascoterone is a newly developed, anti-androgen chemical which is applied topically. In low doses of 1 per cent, it is being explored as a potential acne treatment. However, in larger doses of 2.5 to 7.5 per cent, it is piquing interest as a hair growth product.

As with high strength minoxidil, it is applied directly to the scalp, where it penetrates the skin. It then acts on the androgen receptors located within the sebaceous glands and hair follicles.

Clascoterone Breezula clinical trial results phase 2 male pattern hair loss treatment

Like finasteride 1mg – the oral Male Pattern Hair Loss Treatment for men – Clascoterone is also a DHT blocker. Breezula’s action stops dihydrotestosterone from interacting with specific hair follicles, reducing the likelihood of thinning hair developing.

Increased hair count observed

The 12-month Phase II trial saw 400 men aged between 18 and 55 years old use various doses of Clascoterone. Three groups applied solutions of either 2.5%, 5% or 7.5% Clascoterone twice per day, whilst one group used the 7.5% dose once per day.

A total of 344 participants completed the trial, and the mean data for each group showed an increased hair count during follow-up.

The mean target area hair count increases were as follows: 10.2 for the group using the 2.5% solution, 13.8 for those using 5%, 14.3 for those using 7.5% twice per day and 12.7 for those using the 7.5% solution once per day.

There were also notable mean changes recorded in the target area hair width measurements; these registered as 521.1 for 2.5% users, 615 for 5% users, 762.5 for 7.5% twice per day users and 658.8 for 7.5% once per day users.

Researchers note in regard to the target area hair width data, “highly significant changes vs. vehicle were observed in all active groups with the highest change observed in the 7.5% BID [twice per day] group, which reached borderline statistical significance since the third month (first follow-up visit) and statistical significance at months 6, 9 and 12”.

Furthermore, the results reported an “excellent safety profile”.

Potential benefits for women with PCOS

Commenting on the Breezula clinical trial results, Belgravia hair loss specialist, Rali Bozhinova says, “These results showed statistical significance which of course sounds very promising and I look forward to seeing their future research. It looks like topical Clascoterone is overall well tolerated and is so far showing very positive efficacy on androgen-related conditions such as acne and androgenic alopecia.

Women with PCOS sometimes experience androgenic alopecia, an oily scalp and scalp acne, which are all linked to androgen effects. So, topical Clascoterone may actually be very helpful in such cases.

This study took 12 months but patients with genetic hair loss require ongoing treatment, so I think longer research on the safety of topical Clascoterone will be needed. It will also have to be tested on women.”

Breezula potential release date

In fact, Cassiopea has noted its next steps will be to meet with the FDA in advance of the men’s Phase III clinical trials starting, as well as proceeding with a proof of concept clinical trial in women.

The company’s product pipeline states that it hopes to complete these Phase III trials by 2020, ready for an anticipated launch date of 2022, assuming the MHRA and FDA – and any other appropriate medical regulatory boards – give their authorisations.

For anyone worried about losing their hair now, 2022 – whilst only three years away – is still a long way off. Given Male Pattern Hair Loss is a permanent and progressive condition, those wishing to explore options for stabilising their shedding, promoting hair growth and preventing baldness would be well advised to seek advice now.

Generally, the earlier you can start finding out what works for you, the better the results, when it comes to treating hair loss. There are existing clinically-proven hair loss treatment options which can be paired with additional hair growth supporting products, where appropriate, to form a holistic approach suited to each individual’s medical and lifestyle needs.

Then, if – later down the line – new treatments, such as Breezula, come along and are suitably proven to be safe, tolerable and effective, a specialist will be able to talk you through switching or incorporating it into your current course of hair loss solutions – but at least you’ll have got a head start!


Belgravia Centre Hair Loss Clinic Hair Loss Specialist Free ConsultationThe Belgravia Centre

The Belgravia Centre is an organisation specialising in hair growth and hair loss prevention with two clinics and in-house pharmacies in Central London, UK. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the world. View our Hair Loss Success Stories, which includes the world’s largest gallery of hair growth comparison photos and demonstrates the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time to arrange a free consultation.

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The autoimmune disorder Alopecia Areata can affect men, women and children, causing everything from small bald spots on the scalp only, to complete hairless-ness from head to toe.

Whilst its mildest form may, to some, appear less to worry about, it can still be an incredibly difficult condition to come to terms with, given its unpredictability.

Diagram Belgravia Centre Different Types of Alopecia Areata autoimmune hair loss
Areas affected by hair loss shown in blue

Little is known about its epidemiology, but what is known is that hair regrowth may spontaneously recur at any time. However, if it does, the sudden hair loss may also recur again later.

A study published on 19th March 2019 in the Journal of the European Academy of Dermatology and Venereology may have some encouraging news for those worried by this ‘unknowable’ aspect; researchers have now found that the likelihood of Alopecia Areata relapses may decrease with age.

Frequency of relapses declined over time

A team from the Department of Dermatology at Chaim Sheba Medical Centre in Tel Hashomer, Israel, explored the long-term course of Alopecia Areata by investigating its prevalence in different age groups.

After carrying out a retrospective evaluation of 104 cases of Alopecia Areata – 31 of which started in childhood, 63 were adult-onset and 10 were referred to as ‘late-onset’ – from diagnosis through at least 7 years of follow-up, the team published their findings.

“At first episode, 88.5% of patients had mild, 3.8% moderate and 7.7% severe AA. Full or significant re‐growth was observed in 74%, 94% and 100% of childhood‐onset, adult‐onset and late‐onset AA patients, respectively. There was no re‐growth in 13%, 3% and 0% of childhood‐onset, adult‐onset and late‐onset patients, respectively,” write the study’s authors.

“The duration of the initial episode and the disease‐free interval negatively correlated with age… The frequency of relapses was high overall (52%, 44% and 30% in childhood‐onset, adult‐onset and late‐onset, respectively), but significantly declined over time with a majority (79%) occurring within the first 4 years.”

Researchers confirmed they found no correlation between the relapse rate and gender, how severe the hair loss was, or whether any – or which – treatment was used during the initial bout.

The report concluded that the long-term course of Alopecia Areata appeared to be more positive in older age, stating, “The prevalence of severe disease, duration of an initial episode and the rate of relapses decreased with an older age at onset. In addition, the outcome and the disease‐free interval improved with age at onset. The frequency of relapses declined over time and most appear early on.”

Alopecia Areata hair regrowth

In many cases where Alopecia Areata causes patchy hair loss of the scalp only, hair regrowth will resume naturally within 12 months.

When this hair grows back, it may be paler, white or silver-looking – this is normal and the usual hair colour tends to reappear within a few hair growth cycles.

This spontaneous recovery does not always happen, however, and for those wanting advice on regrowing hair, a consultation with a hair loss specialist can be beneficial.

At Belgravia personalised courses of Alopecia Areata treatment are available to suitable adults; these involve topical high strength minoxidil hair loss solutions which can be used at home.

For children, or those with the more extensive forms of autoimmune alopecia which affect areas other than the scalp, a dermatologist or GP will be able to advise on the best options from potential treatments to emotional and peer support.


The Belgravia Centre

The Belgravia Centre is an organisation specialising in hair growth and hair loss prevention with two clinics and in-house pharmacies in Central London, UK. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the world. View our Hair Loss Success Stories, which includes the world’s largest gallery of hair growth comparison photos and demonstrates the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time to arrange a free consultation.

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A 2017 Phase 2a clinical trial exploring twice-per-day oral doses of setipiprant as a potential treatment for Male Pattern Hair Loss has now published its findings.

Setipiprant is an investigational drug – originally developed as an allergy medication – currently being explored as an antagonist for the PGD2 receptor; the PGD2 receptor is an enzyme that was shown in 2012 to affect hair growth and be an area worthy of study in order for targeted treatments for various hair loss conditions to be developed.

The randomised, multi-centre study was sponsored by Allergan, and pitted setipiprant against finasteride 1mg – currently the only MHRA-licensed and FDA-approved oral men’s hair loss treatment for androgenetic alopecia.

chemical structure of setipiprant

In the results, published on 9th April 2019, some of the data for the finasteride element of the trial has been omitted, however.

Three-arm trial

The double-blind American trial comprised 169 men aged between 18 and 49 years of age, all with a confirmed diagnosis of genetic hair loss.

These participants formed three separate groups, each of which was administered oral tablets for 24 weeks.

One group of 83 men was given setipiprant 1,000mg (2 x 500mg) to be taken at 12 hour intervals, another group of 12 men was given finasteride 1mg to be taken once per day, whilst a further 74 men took a placebo twice daily at 12 hour intervals.

There were a number of participants who did not complete the trial – 26 of those taking setipiprant, 26 of those taking the placebo and 4 from the finasteride group. Reasons ranged from withdrawing consent and not properly complying with the study drug, to adverse events.

As such, the numbers reduced to 78 taking setipiprant, 11 taking finasteride and 70 taking the placebo.

For these men, the following terminal hair counts were recorded in the target area being studied, described as being at the “anterior leading edge of vertex thinning area of scalp and centered with a semi-permanent microdot tattoo to ensure same target area was reproduced each visit”.

Potentially insignificant results

Target Area Hair Count Within Left 1cm^2 Circular Area - Setipiprant Allergan study April 2019
Target Area Hair Count Within Left 1cm^2 Circular Area (in cm^2) After 24 Weeks of Treatment

The changes seen after 24 weeks of treatment, of each type, were measured using digital imaging and the recorded data can be seen in the bar chart, here.

On first appearance, these hair count results look impressive for setipiprant, however, it is only when taking into account the mean data that the true picture emerges. And it is certainly less compelling.

Given the mean is so varied – and the statistical analysis also had a P-value of 0.9239) – this effectively renders them insignificant. This is perhaps why the results were published without fanfare or press release – just yet, at least.

We believe that Allergan is currently waiting for its study to be federally evaluated so, this may also be a reason to delay comment.

To be clear, this does not mean that setipiprant does not show promise as a Male Pattern Hair Loss treatment; what it means is that further research – ideally using better matched participants – is needed to properly establish its potential.

“Although the mean number of hair count per square cm was the highest for setipiprant, the standard deviations were also the highest which suggests the particpants in this group had very different results from each other. Also, looking at the other tables they have provided in their results, their p values suggest the results did not have statistical significance,” says Belgravia hair loss specialist, Rali Bozhinova. “Overall, I think they would need more research, ideally with more participants.”

For now, it remains unproven and far more clinical trials are required if Allergan wishes to meet its current pipeline estimate of a 2021/22 release.


Belgravia Centre Hair Loss Clinic Hair Loss Specialist Free ConsultationThe Belgravia Centre

The Belgravia Centre is an organisation specialising in hair growth and hair loss prevention with two clinics and in-house pharmacies in Central London, UK. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the world. View our Hair Loss Success Stories, which includes the world’s largest gallery of hair growth comparison photos and demonstrates the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time to arrange a free consultation.

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Beating cancer is a huge achievement and relief for many, but this may be marred somewhat for those left with persistent hair loss from chemotherapy.

People who lose their hair during chemotherapy generally see it return to its pre-chemo state within around 12 months of finishing their treatment course. However, as the recent US class action lawsuit regarding the effects of Taxotere – a chemotherapy drug which causes permanent baldness – has brought to the fore, this is not the case for everyone.

A report published in the JAMA Dermatology journal explains the quality of life associated with persistent postchemotherapy alopecia.

Hair growth helped emotional toll

Chemotherapy study

A large-scale, multi-centre review of 192 women experiencing persistent chemotherapy-induced alopecia (pCIA) or endocrine therapy-induced alopecia following chemotherapy (EIAC) examined these individuals’ quality of life, using the Hairdex questionnaire.

Their response to appropriate hair loss treatment was also assessed.

Persistent chemotherapy-induced alopecia was found to often be “more severe and diffuse” compared with EIAC. However, negative quality of life feelings were recorded in both groups. Mild to moderate improvements to these scores were registered following hair loss treatment.

The treatment comprised topical minoxidil – currently a dose-dependent hair loss solution MHRA-licensed and FDA-approved for the treatment of the genetic conditions, Male and Female Pattern Baldness – either on its own or when used alongside orally-administered spironolactone.

Researchers concluded the report, by suggesting “Additional studies are warranted to develop effective strategies for prevention and effective therapy for pCIA and EIAC”.

Treating hair loss after chemotherapy

In cases where hair loss lasts for longer than usual following chemotherapy, and it is upsetting or, as found in the study, having a negative effect on a cancer survivor’s quality of life, a consultation with a specialist is advised.

At Belgravia, our hair loss specialists are happy to provide an assessment and, where appropriate, treatment recommendations to both men and women experiencing these hair regrowth issues.

However, it is important to be aware that in order for any treatment to be prescribed – if it is considered worthwhile – a letter confirming their suitability for this is required from the patient’s oncologist beforehand.


Circ - Belgravia Centre Hair Loss Clinics LondonThe Belgravia Centre

The Belgravia Centre is an organisation specialising in hair growth and hair loss prevention with two clinics and in-house pharmacies in Central London, UK. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the world. View our Hair Loss Success Stories, which includes the world’s largest gallery of hair growth comparison photos and demonstrates the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time to arrange a free consultation.

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Many people know that biotin – vitamin B7 – is one of the key nutrients involved in the maintenance of healthy hair growth.

Low levels of biotin have also recently been implicated in the genetic hair loss condition, Male Pattern Baldness.

Whilst egg yolks are often cited as a go-to food source for biotin, it is important to be mindful as to how many eggs you consume and how often you eat them. This is mainly due to the amount of cholesterol contained in the yolks.

New research published in the Journal of the American Medical Association suggests people should be eating fewer eggs than first thought. This comes at a time where egg consumption has increased due to the food and wellness trend for upping protein intake.

Increased risk of cardiovascular disease

Eggs for Hair Health

Whilst the UK has no recommended daily or weekly limit on eggs, the 2015–2020 Dietary Guidelines for Americans state that dietary cholesterol should be restricted to 300mg/day. In terms of egg yolks, this equates to roughly 1.5 eggs per day, given one large egg contains approximately 200 mg of cholesterol.

This latest study into the effects of cholesterol specifically from eggs, and egg yolks, on the potential for heart disease found that consuming 300mg/day of dietary cholesterol resulted in a 17 per cent increase to the risk of developing cardiovascular disease and an 18 per cent higher risk of death in general. For those eating three to four eggs per week, there were links to a 6 per cent increased risk of cardiovascular disease and an 8 per cent risk increase of dying from any cause.

One of the study authors, Norinna B. Allen PhD, advised: “Our study showed if two people had exact same diet and the only difference in diet was eggs, then you could directly measure the effect of the egg consumption on heart disease. We found cholesterol, regardless of the source, was associated with an increased risk of heart disease. We want to remind people there is cholesterol in eggs, specifically yolks, and this has a harmful effect”.

Non-egg dietary sources of biotin

Whilst eggs are affordable, nutritional powerhouses and should not be avoided, those wishing to switch up their dietary source of biotin, here are a few examples of foods rich in the hair-friendly vitamin…

Almonds – whilst many nuts are a good source of biotin, almonds pack the biggest punch, whether raw, roasted or salted, with 1.5mcg per 32g serving.

Avocado – in addition to being a great source of vitamin E, one whole avocado will provide approximately 2 to 6 mcg of biotin, depending on its size.

Hair Vitalics for Women and Hair Vitalics for Men healthy hair supplement hair specialist Belgravia Centre

Cauliflower – 128 g / one cup raw cauliflower can provide 4 mcg of biotin, whether eaten as crudities or uncooked cauliflower rice.

Liver – a 3 ounce serving of cooked beef liver contains approximately 30mcg of biotin, making it one of the richest food sources available.

Nutritional Yeast – also known as ‘nooch’, nutritional yeast is a popular vegan condiment that is a good source of B vitamins, including biotin.

Sunflower Seeds – these small but mighty seeds are jammed with nutrients, including magnesium, iron, calcium, zinc and copper, as well as 2.6mcg of biotin per 32 gram portion.

Sweet potato – this root vegetable are a good source of vitamin A, potassium and, offer 2.4mcg per 64g serving of biotin when cooked.

The recommended daily intake for biotin is 40mcg a day for adults, though several studies have found no adverse effects or symptoms of toxicity occur when taking higher doses.

Oregon State University research states that biotin is “well-tolerated” in doses of 200mg per day, and these were not associated with adverse affects, despite being “nearly 7,000 times” the adequate intake.

Whilst no substitute for a varied and balanced diet, food supplements can be a convenient top-up. Belgravia hair specialists have developed exclusive, one-a-day Hair Vitalics food supplements in specific Men’s and Women’s formulations, which contain a custom blend of vitamins, minerals, amino acids and botanical extracts – including biotin – to support normal healthy hair growth. These are one of the products available to non-clients, as well as patients of Belgravia hair loss clinics.


The Belgravia Centre

The Belgravia Centre is an organisation specialising in hair growth and hair loss prevention with two clinics and in-house pharmacies in Central London, UK. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the world. View our Hair Loss Success Stories, which includes the world’s largest gallery of hair growth comparison photos and demonstrates the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time to arrange a free consultation.

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According to a market research report regarding the treatment of Tinea Capitis – ringworm of the scalp – this infection is on the rise.

Data provided by the Industry Daily Observer as part of the research report ‘Tinea Capitis Treatment Market – Global Industry Trend Analysis 2013 – 2017 and Forecast 2018 – 2026’ showed the condition is having a global uptick.

Luckily, there are various treatment solutions available for this scalp condition, which is often accompanied by areas of hair loss.

Tinea Capitis - Scalp Ringworm - Hairloss - Children
An example of Tinea Capitis

More prevalent in boys

Tinea capitis generally affects prepubescent children aged between 3 and 10 years old, though it can also affect post-menopausal adults who are caretakers of young children.

It is more commonly found in urban areas and displays as rounded scaly, flaking patches of skin with fine hair loss and black dots, which can be hard to spot when mild.

It is a fungal or dermatophyte infection which tends to be more prevalent in boys than in girls. There are two key dermatophytes which tend to cause the majority of cases, Microsporum spp. and Trichophyton spp.

Whilst Microsporum canis is the most common cause of European cases – particularly in Mediterranean border countries, Trichophyton tonsurans are described as being “highly prevalent” in the UK, reportedly accounting for 50-90 per cent of diagnoses.

Microsporum canis is a fungus which can infect the upper layers of the skin of domesticated cats. It can also be found in the skin of dogs and humans; as such, it is largely passed on by animals, especially puppies and kittens.

child baby toddler bubble bath hair wash

Trichophyton tonsurans is a fungus said in a Pediatric Clinical Advisor report in 2007, to be responsible for 95 per cent of Tinea Capitis cases in North and South America. The new report advises that “ethnicity, social as well as cultural factors are registered to play an important role” in its spreading among black communities across Europe and both North and South America.

General factors involved in catching tinea capitis include overcrowding, schools, hairdressing salons and sharing combs.

Anti-fungal treatments

Tinea capitis is usually treated using anti-fungal therapies, whether oral or topical and treatment tends to be fairly short-term – usually daily for a matter of weeks.

Some of the more popular options include oral ketoconazole, medicated ketoconazole or selenium sulfide shampoo, and miconazole antifungal cream. The strength and frequency of use will be determined by the professional prescribing treatment, including options which are available over-the-counter, and is based on factors including the child’s age and overall health.

The market report states that “In the United States, the prevalence of Tinea capitis ranges from 3%-13%, that is expected to drive the demand for antifungal therapy in Tinea capitis treatment market. However, incidence for Tinea capitis is lowest in Spain and Palestine (<1%) and is highest in Ethiopia (~50%).”

Due to the fact this condition almost exclusively affects young children, Belgravia does not offer treatments for Tinea Capitis. Anyone concerned about this infectious condition should approach their GP or dermatologist for assistance.


The Belgravia Centre

The Belgravia Centre is an organisation specialising in hair growth and hair loss prevention with two clinics and in-house pharmacies in Central London, UK. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the world. View our Hair Loss Success Stories, which includes the world’s largest gallery of hair growth comparison photos and demonstrates the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time to arrange a free consultation.

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The International Society of Hair Restoration Surgeons (ISHRS) has launched a campaign to warn people of the dangers associated with getting a ‘black market’ hair transplant.

In a shocking press statement from March 2019, the industry body advised that 77.5 per cent of its members – qualified hair restoration surgeons – have seen an increase in the number of people coming to them for help after ‘botched’ procedures.

The reason for the number of poor results has been put squarely at the door of illegal hair transplant clinics, and poorly trained – or completely unqualified – non-medical practitioners carrying out these highly skilled procedures.

The ISHRS reports that, due to the demand for hair transplants, often cheap ones carried out abroad, and unscrupulous attempts to cash in on people’s hair loss concerns, they have even heard of instances where the operation has been carried out by a taxi driver.

Disfiguring results, scarring and infections

ISHRS members reported cases where post-op patients of these dubious ‘clinics’, presented to them with scarring and infections, over-harvesting – where too much donor hair has been removed, leaving the area bald with little hope of there being enough to use for any corrective procedures – and infections.

Additionally, poor results such as “disfiguring” unnatural looking hairlines and follicles being placed so that grafted hair grows in the wrong direction, were obvious.

Another issue the medical association feels potential customers, particularly those seeking a hair transplant abroad and looking into medical tourism, should be aware of is inaccurate graft counts.

The cost of hair transplants tends to be worked out based on the number of grafts, which is essentially a per-hair price. The ISHRS advised that patients have been booked in – and charged for – a specific number of grafts, but in reality have received around half that amount.

When having medical procedures in a foreign country, whilst their marketing may be sophisticated, including online reviews which cannot be easily verified by the viewer, the reality can often include poor-to-no aftercare and language barriers, making it hard to address any concerns or pursue recourse.

This is, of course, in addition to any issues with the conditions of the clinic and its equipment, not to mention ensuring the staff carrying out your operation are properly, medically trained and have the relevant skills and qualifications.

One way to avoid falling into the black market hair transplant trap is to check the ISHRS website – ishrs.org – to verify credentials for a specific clinic and/or surgeon, before going ahead.

“This is a serious crisis for anyone seeking help for hair loss, which is why the ISHRS is working diligently to educate patients about these dangers. We have many competent doctors in the ISHRS operating in the medical tourism industry who have signed a commitment that the Doctor does the surgery and have attended educational meetings regularly to assure the hair restoration surgery in the end makes you happy and not one you will regret for a lifetime,” says Ricardo Mejia, MD, chair of the ISHRS Committee on Issues Pertaining to the Unlicensed Practice of Medicine.

Non-surgical alternatives

Unethical hair restoration practitioners are unlikely to provide unbiased advice when it comes to dealing with hairloss.

It is likely a hair transplant is neither necessary nor appropriate for certain levels of Male Pattern Baldness, or for men who are under 30 years old.

Where there is a drop in hair density and thinning hair or a receding hairline but the hair is still present – the scalp has not yet taken on the smooth, shiny look associated with going bald – non-surgical hair loss treatment is generally the first step to consider.

Many top surgeons advise men considering hair replacement surgery to first follow a course of clinically-proven hair treatments – high strength minoxidil and/or finasteride 1mg – for a minimum of 6 to 12 months.

Doing so will give the candidate an idea of what can be achieved without surgery but, should they still decide to go ahead with the op, they will have maximised their hair growth and stabilised hair fall in preparation for the procedure. This is likely to lead to better results as it gives the surgeon more to work with, as well as a cleaner area with less shedding to deal with.

For those who have a hair transplant, aftercare is critical in maintaining the results obtained, which should become fully realised around 12 months post-op. Continuing to follow this type of pharmaceutical hair loss treatment programme, with additional hair growth supporting products where desired, plays a big role in preventing baldness around the grafts.

When choosing a surgical practitioner or hair loss specialist, it is vital to not only do your research, but to meet with a number of different businesses in order to make an informed decision.

Dealing with hairloss can be a tough and emotional ordeal so, once you know they are properly qualified and equipped to meet your needs, go with the professionals you feel most comfortable dealing with and will be comfortable about reaching out to for help, should you need it.


The Belgravia Centre

The Belgravia Centre is an organisation specialising in hair growth and hair loss prevention with two clinics and in-house pharmacies in Central London, UK. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the world. View our Hair Loss Success Stories, which includes the world’s largest gallery of hair growth comparison photos and demonstrates the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time to arrange a free consultation.

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Football superstar Cristiano Ronaldo has invested in a hair transplant clinic in Spain.

When the deal was announced, many European media outlets questioned if it was a a ‘try before you buy’ scenario and whether Cristiano Ronaldo has had a hair transplant himself.

After all, at 34 years of age, the Portugal captain is in a prime period for developing Male Pattern Baldness should he have the relevant genetic predisposition.

Did Cristiano Ronaldo have a hair transplant?

cristiano ronaldo have a hair transplant clinic open spain hair loss footballer

The Juventus forward did not answer the question head-on, but rather stated, “Everyone likes to take care of their image and I am a very clear example of this.” He also added, “When I think it’s necessary, of course, I’ll do it. One’s image is an essential tool for being successful. For me, it’s fundamental.”

Having maintained an impressive, seemingly thick head of jet black hair with a strong hairline throughout his career, many online hair loss forum users have debated whether the highest European international goalscorer of all-time has been taking steps towards preventing baldness.

There are two clinically-proven, MHRA-licensed and FDA-approved Male Pattern Hair Loss Treatments which are both permitted for professional footballers to use, and do not involve taking a surgical approach.

These are the one-a-day DHT-blocking tablet, finasteride 1mg, and topical solutions of high strength minoxidil. They inhibit the hormone which causes thinning hair and, often, eventual baldness in affected men, and promote accelerated hair regrowth, respectively.

In addition to these medications, additional hair growth supporting products such as FDA-cleared low level laser therapy (LLLT) devices – the home-use LaserComb or LaserBand, for example – and highly-targeted food supplements, like Hair Vitalics for Men, can be used. These can form part of a tailored, fully-rounded approach to preventing hair loss, optimising the hair’s condition and helping men to avoid hair transplant surgery.

It may be the case that the player has been using treatments such as these, or boosting his natural hair density with microscopic hair fibres – as his footballing friends David Beckham and Wayne Rooney are rumoured to – but he has neither confirmed nor denied this on-going speculation.

Improve self-esteem

Ronaldo – who has previously let slip his knowledge of hair restoration surgery when joking about changes in former Real Madrid goalkeeper, Diego Lopez’s receding hairline – says he wants to help people experiencing hair loss to improve their self-esteem.

“Alopecia is a very big problem in Europe and around the world and we want to help people improve their self-esteem and not be ashamed to come to us,” the former Manchester United star said at the clinic’s opening.

Hair loss is known to cause a drop in people’s self-confidence so this sentiment is laudable, but Ronaldo’s use of the term ‘alopecia’ appears – not for the first time – to have confused some journalists.

The word ‘alopecia’ simply means ‘hair loss’ but does not specify a particular hair loss condition; reporters in publications including Goal.com have confused this with Alopecia Areata, an autoimmune disorder which causes varying amounts of sudden hair fall. It can result in rounded bald spots on the scalp only, all the way through to complete baldness from head to toe.

What tends to be meant in reports such as this, and without doubt in the case of Ronaldo’s statement given hair transplants are not suitable treatment for Alopecia Areata, is Androgenetic Alopecia, which is the medical term for Male Pattern Baldness and Female Pattern Hair Loss. Both these hereditary conditions involve permanent, progressive hair thinning affected the area along the top of the scalp from hairline and temples to crown, only.

Hopefully, despite the apparent mix-up by reporters, anyone worried about losing their hair should still feel comforted by the footballer’s words which may help to further remove the perceived stigma surrounding dealing with hair loss, even if it doesn’t involve surgery.


Belgravia Centre Hair Loss Clinic Hair Loss Specialist Free ConsultationThe Belgravia Centre

The Belgravia Centre is an organisation specialising in hair growth and hair loss prevention with two clinics and in-house pharmacies in Central London, UK. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the world. View our Hair Loss Success Stories, which includes the world’s largest gallery of hair growth comparison photos and demonstrates the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time to arrange a free consultation.

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Scalp injections are all the rage when it comes to treating genetic hair loss, despite the lack of evidence concerning their efficacy as a standalone treatment.

From mesotherapy to PRP, both men and women are turning to what many assume to be a ‘quick fix’ hair loss solution, in a bid to combat their thinning hair, even though these purported scalp injections for hair regrowth are required regularly as part of an on-going treatment programme.

These minimally invasive therapies are not a ‘one and done’ remedy and many trial results appear to suggest they should be classified as a hair growth support rather than a solo, front-line hair loss treatment.

However, due to the rising popularity of injectable treatments for Male Pattern Baldness and Female Pattern Hair Loss, many variations are being explored, the latest of which features cells derived from the patient’s own body fat being injected into their scalps.

White Adipose Tissue
White Adipose Tissue

Using body fat-derived cells to stimulate hair regrowth

Colorado, USA-based cellular medicine company, the GID Group first registered its intentions of carrying out a small scale clinical trial investigating a specific, single scalp injection within a six month period, as a treatment for androgenetic alopecia, in December 2015.

The aim was to determine whether or not adipose-derived stromal vascular fraction (SVF) injections in patients scalps could stimulate hair regrowth in cases of Male and Female Pattern Baldness.

These involved harvesting a small amount of the patient’s body fat (adipose) using liposuction, from which SVF was derived. SVF is known to contain various cell populations. These may have beneficial regenerative properties, which the researchers hoped may stimulate hair regrowth when injected into a 2cm x 2cm area of the trial participants’ scalps.

After carrying out a six month trial, comprising just seven participants aged between 18 and 65 years of age – three of whom withdrew from the exercise, leaving four subjects from whom to draw conclusions – the results were published on 21st March 2019.

The primary objective was to establish the safety of the treatment by monitoring for any adverse events, whilst the secondary measure was to assess new hair growth by comparing the number of hairs each participant had before and after the trial.

Results show increased hair growth

The four American participants – two male, two female – who completed the full trial had a mean age of 41 years.

Before being administered their treatments, each individual’s level of hair loss was categorised using the Norwood scale for men and the Ludwig scale for women. Information as to how extensive each volunteer’s hairloss was, was not made public, however.

No incidences of adverse reactions – side effects, from minimal to serious – were reported during the process.

Increased hair density was seen among the participants, with published results stating that all four achieving a mean 31 per cent gain in the number of hairs per square centimetre, when comparing their hair count and hair thickness from before the trial and at six months after the SVF treatment.

Whilst this data is certainly encouraging, the fact that only four people took part in the trial means there is not sufficient clinical evidence to make a true evaluation.

It is a good starting point for further investigation, with wider-ranging, larger-scale trials likely to give a more thorough picture from which to decipher whether or not this therapy has legs as a potential safe and effective genetic hair loss treatment for both men and women.

Furthermore, optimal doses, regularity of treatment and the amount of hair loss which it could treat would all need to be established, as well as whether it is best used on its own, or in addition to the existing MHRA-licensed and FDA-approved hair loss treatment options, currently available.

For now, anyone wanting to explore options for regrowing hair and preventing baldness is best advised to start by having a consultation with a specialist who can make tailored recommendations based on condition, level and pattern of shedding, as well as the individual’s personal medical requirements.


The Belgravia Centre

The Belgravia Centre is an organisation specialising in hair growth and hair loss prevention with two clinics and in-house pharmacies in Central London, UK. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the world. View our Hair Loss Success Stories, which includes the world’s largest gallery of hair growth comparison photos and demonstrates the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time to arrange a free consultation.

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Many of us pay attention to our hair care routine, from how often we wash our hair, to the products we use and being careful to avoid wearing hairstyles that may lead to hair loss too often.

One thing that can be neglected, however, is hair tools – particularly your hair dryer.

If you aren’t vigilant in practising good hairdryer maintenance, it could be the reason your hair takes longer to dry, or even cause the appearance of thinning hair.

Taking care of your hair dryer

hair dryer hairdryer heat styling hair care breakage heat damage hair

Hair dryers vents can easily build up stray dust and shed hairs, especially if hairsprays or other sticky products are used nearby, causing them to become blocked.

Clogged vents in hairdryers – especially with older models or more classic designs – can lead to overheating which can cause a number of problems; in particularly bad cases your hair dryer may stop working or you may smell burning whilst using it.

Although this is generally due to the debris caught in the vents overheating, the machine itself may well catch fire. Furthermore, in addition to damaging the machine itself, it can also be harmful to your hair as it becomes too hot.

As vents become blocked, proper air flow becomes increasingly difficult, causing the temperature of the hair dryer to rise, and hair drying times to become longer due to the machine’s hindered efficacy.

Heat damaged hair can become weak and brittle; this can then result in split ends, or snap along the shaft which can make the hair look thin and limp. This is known as hair breakage.

To prevent hair breakage and issues with your dryer, clean out the air vents regularly so that build-up is minimised. Also, ensure you use the medium heat setting on your hair dryer to reduce the risk of heat damage, especially if you blow dry your hair regularly.

How to restore heat damaged hair

Hair breakage affects the lengths of the hair, not the follicles. As such, this is considered hair damage rather than a hair loss condition.

hair vitamins nutrition Hair Vitalics for Women and Hair Vitalics for Men healthy hair food supplement hair specialist Belgravia Centre

Therefore, if you have damaged hair, a trip to the hairdresser or barber should be sufficient to help you restore heat damaged hair. A haircut and regular nourishing hair treatments, such as conditioning masks to strengthen and hydrate the hair, should have your hair looking and feeling better fairly quickly.

You can also ensure your hair has a good source of key nutrients needed for healthy hair growth – these include biotin, selenium and zinc. Whilst not intended to replace a balanced diet, these crucial ingredients, and many more vitamins, minerals, amino acids and botanicals can be found in Belgravia’s exclusive Hair Vitalics food supplement.

If the breakage is extensive or accompanied by sudden or excessive shedding or obvious hair loss, a consultation at a dedicated hair loss clinic is advisable. That way, a specialist can assess your scalp – either in person or using photos uploaded to an online consultation form – and provide you with both a diagnosis and, where appropriate, hair loss treatment recommendations, based on their findings.

Whichever route you take, the first step is to stop using any heat-styling tools – such as your hair dryer, hair straighteners (flat irons), curling tongs or even heated hair brushes – and let your hair dry naturally whilst it recovers.


The Belgravia Centre

The Belgravia Centre is an organisation specialising in hair growth and hair loss prevention with two clinics and in-house pharmacies in Central London, UK. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the world. View our Hair Loss Success Stories, which includes the world’s largest gallery of hair growth comparison photos and demonstrates the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time to arrange a free consultation.

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