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People are often interested in knowing about the links between diet and hair loss, focusing on food and nutrient intakes – but what we drink can be equally as important.

Water is vital for the proper functioning of numerous bodily functions, including the hair growth cycle. However, a 2015 survey by the Royal National Lifeboat Institution found 89 per cent of UK adults were drinking less than the recommended 2 litres per day required for good hydration. Shockingly, 13 per cent of women and 20 per cent of men said they drank no water at all.

Whilst alcohol has a generally drying effect on the body, it is not considered significant in relation to hair loss when consumed responsibly and in moderation. If alcohol consumption turns to alcoholism, where there are regular patterns of excessive intake, this can be an issue, leading to dry, weakened and thinning hair.

Stress alcohol drinking health male hair lossNow, new research has discovered that even a single session of binge drinking, involving four alcoholic drinks consumed in one sitting, can cause sleep problems known to contribute to hair loss.

Sporadic excessive alcohol consumption

Data released by the Office for National Statistics regarding the 2017 drinking habits of adults in Great Britain shows that 29.2 million people drink alcohol in the UK. It states that men (61.9%) are more likely to drink than women (52.4%), with the 45 to 64 years age group having the highest alcohol consumption levels. When it comes to the 16 to 24 year old age group, although this has the lowest levels of alcohol consumption, it is also the category most likely to binge drink, with their heaviest drinking days being higher than those seen among other age brackets.

Binge drinking among those aged 65 years and older was the least prevalent, though men in this demographic (14.7%) were almost twice as likely as women (7.6%) to participate when they did indulge.

The report states: ‘The generally higher levels of binge drinking among those aged 16 to 24 years could be due to the data capturing those who tend to drink excessively on Friday or Saturday nights and then not much else during the rest of the week.’

In the USA, it is estimated that one in every six adults binge drinks at least four times per month, according to its Centers for Disease Control and Prevention.

Effects of binge drinking on sleep

Research from May 2018 published in the Journal of Neurochemistry shows how researchers from the University of Missouri – Columbia, USA, explored the effects of binge drinking on sleep patterns.

Through conducting mice trials, it was established that just one session of binge drinking – where at least four alcoholic drinks were consumed in one session – was sufficient to down-regulate a crucial gene involved in achieving restful sleep. This is known as the equilibrative nucleoside transporter 1 (ENT1) and meant that sleep disturbances could occur a result.

The Futurity.org website quotes the study’s lead author, professor and director of research at the University of Missouri School of Medicine’s neurology department, Mahesh Thakkar commenting on this work.

woman smoking smoker stress hungover hangoverSleep is a serious problem for alcoholics,” he says. “If you binge drink, the second day you will feel sleep deprived and will need to drink even more alcohol to go to sleep. It is a dangerous cycle. How can we stop this cycle or prevent it before it begins? To answer that question, we need to understand the mechanisms involved. What we have shown in this research is that a particular gene—which is very important for sleep homeostasis—is altered by just one session of binge drinking,” Thakkar says. “We were not expecting this. We thought it would be affected after multiple sessions of binge drinking, not one. That tells you that as soon as you consume four drinks, it can alter your genes.

Sleep disruption and hair loss

Thinning hair in men and women has been linked to regular sleep deprivation due to the physical internal stress this can place on the body.

In addition to exacerbating existing cases of Male Pattern Baldness or, the women’s equivalent, Female Pattern Hair Loss, it can also prematurely trigger these hereditary conditions in people with an underlying genetic predisposition. Furthermore, it can cause the temporary conditions Telogen Effluvium – which presents as up to 60 per cent hair rapidly shedding from all over the scalp and lasts around six months – or the chronic form, Diffuse Thinning, which can last longer.

On-going problems with sleep disruption have also been linked to a higher chance of developing diabetes – a health issue also known to cause hair loss as a side effect. It is also more likely to lead to unhealthy food and lifestyle choices, including smoking.

Whilst there are hair loss treatment solutions available for all these different conditions, prevention is certainly possible in many cases. When visiting Belgravia for a consultation, a hair specialist will discuss your lifestyle in addition to taking a medical history, in order to see if there any issues that may be contributing to excess hair fall, and a balanced lifestyle – including healthy eating, regular exercise and solid stress management – are always advisable.


circ - Mens and womens hair vitamins Hair Vitalics for Men Women Belgravia Centre hair growth supplementThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


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The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) has issued a warning regarding the storage of head lice medications.

Further to a Drug Alert sent to pharmacists urging them to make people purchasing such treatments aware of the risks, the MHRA states in a public press release: ‘Parents, caregivers and people with head lice are being reminded to always read product instructions before applying head lice removal products. Some of these products have the potential to ignite when in the presence of an open flame – such as when lighting cigarettes.’

The warnings come after 10 incidents of serious burns associated with head lice treatment – which can ignite whilst on the hair – were reported to the MHRA during the 2007 – April 2018 period.

itchy head scalp hair lice nitsProper storage of hair treatments

Head lice treatments are not the only type of medication which needs to be properly stored. The patient information leaflet which accompanies all medications should contain the relevant instructions for safe storage and – as with the rest of the directions contained – it is important to follow them.

Hair loss treatments are no exception when it comes to following proper storage protocols, though the rules, such as keeping bottles away from direct sunlight, generally have little impact on users. They mostly refer to how topical hair loss solutions in particular are stored by manufacturers, pharmacists and sellers and set out practices to ensure the products remain at their optimum efficacy, and that safety is not compromised.

Along with not knowing precisely what the packaging may contain or whether it is in date, this storage issue is one of the key troubling factors people should be wary of when considering buying hair loss medications from unauthorised vendors or websites. The MHRA has previously run campaigns advising people about the dangers associated with buying counterfeit or stolen medications.

Hair loss from scalp burns

Should anyone find themselves in the unfortunate position of burning their scalp, either the emergency services or their GP – depending on the severity – will be able to assist with pain management and healing. Whether hair loss as a result of scalp burns will be permanent or not depends on how acutely the hair follicles have been affected.

If it is a minor, surface burn then, once the scalp heals properly, as long as there is no scarring, normal hair growth should resume within a few months. Where there is scarring and the skin takes on a smooth, shiny appearance, this is a sign that the follicles are no longer functioning so hair growth is no longer possible, even with the help of pharmaceutical treatments. In this case, the resulting hair loss condition is called Cicatricial Alopecia, also known as Scarring Alopecia.

In some cases surgical hair restoration may be a possibility, though as burns vary so drastically from person to person, as well as the level and quality of donor hair – the hair that is taken from the back and/or sides of the head and grafted into the recipient areas of the scalp during a hair transplant – this is decided very much on a case-by-case basis. There are various surgeons in the UK with highly specialised expertise in this area and anyone considering this option would do well to take advice from one of these renowned experts to gauge whether this is the right procedure for them and if it is likely to be successful.


circ - Belgravia Centre hair loss clinic London pharmacy hairloss treatmentsThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


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Dealing with hair loss is something different people tackle in different ways. For Lauren Marcus, the star of cult Young Adult off-Broadway theatre show, Be More Chill, it involved writing a song.

Be More ChillCalled ‘Funeral’ the song explains her feelings about losing her hair to the autoimmune disorder Alopecia Areata.

She has also spoken openly about the recent and sudden loss of ‘99.7% of the hair on [her] head’ in social media posts and in an article written for Yahoo Lifestyle.

Explaining Alopecia Areata

Lauren Marcus has an acute form of the disorder which has affected the hair follicles on her scalp and parts of her body, resulting in patchy hair loss but without the loss of her eyebrows and eyelashes.

She tries to be positive about managing this new issue and is clear about the importance of talking candidly about Alopecia Areata in order to educate people and raise awareness. This is especially important given the hairloss the condition causes can often, upsettingly, be mistaken for cancer – something people with all forms of autoimmune alopecia frequently point out.

Writing in Yahoo Lifestyle, she says,”A lot of times I’ll be out and if I’m not wearing something around my head, I’ll hear little kids ask their parents, “Why does that girl have no hair?” And they’ll tell their kids to shut up and walk away, and I want to try to explain. Often people assume I have cancer. They’ll come up to me and tell me their stories, and when I say I have alopecia, they’ll say something like “Thank your lucky stars you don’t have cancer!” Of course I’m grateful that I don’t have cancer. But I’m still allowed to be upset that all my hair fell out.” Continues below…

Woof. Okay. So…ready? Here goes. (Please excuse the lack of paragraph breaks here, and head to FB if you need more writing-clarity…don’t have the patience to figure out how to put ’em in here!) I lost all my hair, guys. Like all of it except for a few itty bitty strands that were starting to make me feel like an old man with a bad combover. And then last night around midnight I decided to shave the rest of it off with the help of one of my best friends, who just so happens to be in St. Louis with me (thank god), working on another show while I work on THE HUMANS. (If you’re anything like me, at this point in the post you may have just gone to my FB photos and scrolled through to see if you could detect any signs of hair loss over the last several months or years. If so, I admire your internet sleuthing ways!) The short version of the very, very long story is that I have alopecia. And because I just couldn’t stop there, my body went the rarer route and developed “acute alopecia areata”. This is A BRAND. NEW. LIFE. DEVELOPMENT. It began with a bald spot–I’m not kidding–two days before COMPANY opened in August, and progressed to me losing 99.7% of the hair on my head by yesterday. Most of it left me over Christmas. These have been five of the hardest, scariest, and more bizarre months of my adult life, and I am still figuring it out as I go, you know? AND IT’S STILL HAPPENING! What’s next? Eyebrows? Eyelashes?? Who’s to say?! When I’m back in March, if you have questions, we can talk allllllll about it then. I LOVE to talk about it! And Joe Iconis, the most supportive and loving husband in the goddamn WORLD (and who, ironically, has absolutely said to me in years past–more than once–that he finds bald women very attractive) will probably be beyond excited for me to have someone else to discuss every tiny, alopecia-ridden detail of the whole affair with. [CONT IN COMMENTS]

A post shared by Lauren Marcus (@laurmarcus) on


Will only wear a wig whilst performing

Whether or not to wear a wig can be a bigger decision for people who have lost their hair – for whatever reason – than some may appreciate. For Marcus she says that, as her Be More Chill character – Brooke – has long blonde hair, as she used to, she will wear a wig on stage to continue to play the role. The feeling of having no hair of her own to flip, as required in the script, initially provided a painful reminder of what she was missing for the musical theatre actress, she admitted.

Off stage Lauren Marcus wears hats and scarves to cover her head, as well as rocking her natural bald look. She will not, however, wear a wig in her private, everyday life citing feeling uncomfortable about people who remember what she looked like with hair seeing her in a wig as the reason she isn’t considering this option for now.

Although she she is clear that she didn’t exactly sign up to be an Alopecia Areata spokesperson, she says being able to make an impact and help fans who reach out to her about their hair loss, does make her happy. “Even a few months ago I was frantically Googling, looking for somebody, some other actor, who’d had this and was open about it so I wouldn’t feel so alone,” states Marcus.

She now joins a list of hugely successful, inspirational actors and athletes who are also keen to help others dealing with alopecia. This includes comedy actor Matt Lucas, action movie and Dumbo star Joseph Gatt, Gotham and Barry henchman Anthony Carrigan and gold medal-winning Olympic cyclist Joanna Rowsell-Shand.

Whilst Alopecia Areata treatment is possible for the scalp-only form for medically-suitable over 16s, most of these celebrities have the most severe form, Alopecia Universalis, which cannot yet be effectively treated, though many proposed treatments are in development.


Circ - Minoxidil iconThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


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Belgravia Centre Hair Loss Treatment Before and After Results - New Success Story

alert female pattern hair loss chronic telogen effluvium the belgravia centre 19 07 2018A new entry has just been added to Belgravia’s Female Pattern Hair Loss Treatment Success Stories gallery.

Miss S, pictured, has two separate conditions – Chronic Telogen Effluvium and Female Pattern Hair Loss which are being treated simultaneously, thanks to a personalised treatment plan, based around a high strength minoxidil product available from Belgravia, as devised by her dedicated hair specialist.

Find out what she had to say and see her regrowth results close up, or find out more about treating hereditary hair loss in women by clicking the buttons below…

(Results may vary and are not guaranteed)

 

View succeSS STORY

CHRONIC TELOGEN EFFLUVIUM TREATMENT 

FEMALE HAIR LOSS TREATMENT 

 


The Belgravia Centre Hair Loss ClinicThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


Model and TV personality, Abbey Clancy has opened up about experiencing pregnancy hair loss and the effect it has had on her confidence.

The 32 year old told Closer magazine that her hair was falling out not only after giving birth to her third child, but also throughout her pregnancy.

Abbey Clancy instagramPost-partum alopecia and pregnancy hair loss

My hair was falling out throughout my whole pregnancy with baby Johnny – and still is now, so it’s fallen out loads,” Clancy told Closer. “Every day I’m like, ‘My hair’s thinner and thinner’ – so that’s hard and it does knock your confidence“.

The hair colour brand spokesmodel added, “I didn’t dye my hair during pregnancy and it went quite dark but, as soon as I had the baby, I wanted to go blonder and feel more like me and get back my confidence.

At any one time around 90 per cent of scalp hair is actively growing (the Anagen stage), whilst 10 per cent is in the ‘resting’ (Telogen) stage of the hair growth cycle; this is the penultimate stage before hair sheds ready for the cycle to repeat. Generally during pregnancy the Anagen phase is extended, meaning that the hair grows for longer and sheds less than normal. Once the baby has been born and hormone levels return to normal, the Telogen phase kicks in and the hair begins to fall; this is the entirely normal process known as post partum alopecia.

Whilst post-partum alopecia is a well-documented phenomenon experienced by many women around three months after having given birth, it is less common for hairloss to occur whilst a woman in pregnant. However, due to hormonal fluctuations, it is entirely possible for a couple of different hair loss conditions to occur.

The first, and the one it seems may have affected Abbey Clancy, is a form of temporary hair loss known as Telogen Effluvium. This presents as thinning hair all over the scalp and tends to last no more than six months, though if it does it may be chronic, though this is still a temporary issue. This can also occur if there are any underlying health issues set of or exacerbated during pregnancy, such as additional thyroid issues, for example.

The second is Alopecia Areata, an autoimmune disorder which can be triggered by hormonal changes and presents as patchy hair loss forming bald spots on the scalp. This is rarer and does not match the description of thinning hair given in Clancy’s interview.

Thinning hair regrowth after giving birth

The former Strictly Come Dancing star is one of a long list of new mums, from Britt Ekland to Cheryl Tweedy, to speak out about thinning hair following pregnancy.

Hair loss treatment cannot be used during pregnancy, however, once a woman has given birth and finishing breastfeeding or expressing milk, this option opens up to her. Usually the hair returns to normal naturally within 12 months of postnatal alopecia developing, though treatment can be used to help expedite this process. This approach often involves the application of a topical medication bolstered by the use of appropriate, key hair growth supporting products.

One thing Belgravia hair specialists would caution against is wearing hair extensions in order to make the hair appear fuller – something Abbey Clancy, like many celebrities, has been known to do. Whilst wearing extensions – whether bonded, sew-ins, clip-ins or tape-ins – can provide the hair with extra volume, the additional weight and tension they cause can damage hair follicles. This can lead to hair breakage – where the hair becomes so weak that it snaps along the shaft, leaving it looking frizzy and thin – and/or hair loss from Traction Alopecia.

Anyone concerned about excessive hair fall, whether they are pregnant, have recently had a baby or not, should consult a professional at the earliest opportunity. This will not only provide them with the peace of mind that can come from having an expert diagnose their condition, but  it can also arm them with the necessary knowledge regarding treatment options that’s needed to make an informed decision about how to proceed.


circ - The Belgravia Centre Hair Loss Clinic - For Men and WomenThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


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“Marina was polite and very helpful. Explained what she was doing and why when examining my hair, answered my questions and my concerns. She explained the alternative treatments very clearly, particularly liked the way there was no hard sell. Farzana was polite and very helpful. She explained the alternative ways of billing etc very clearly. Like Marina, a very pleasant person to deal with and again, no hard sell. Receptionists were helpful and polite. The appearance and atmosphere of the clinic was very good, relaxed but efficient.”

Belgravia Centre Consultation Comments Reviews

“I found Marina to be very helpful and informative. She made me feel at ease and was very professional. Cherie was very professional and got straight to the point (which is what I wanted). All the ladies on reception seemed very helpful and friendly. Good location for me coming from Liverpool Street. Pleased you use bags which do not advertise the centre.”

“Saive was a very approachable and friendly hair specialist, she answered all my questions and helped me to chose what is good for my case.  Very professional and honest person, thank you Saive. Thank you to Cherie for her assistance. Big thanks to the reception team, very friendly and professional staff with the smile on all the time, it made me feel very comfortable from the time I stepped in. Warm place very clean and calm with nice staff and various selection of drinks for all patients.”


circ - Belgravia Centre hair loss clinic London pharmacy hairloss treatmentsThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


HairlossANSWERS - Click to Submit Your Query to Our Hair Loss Experts

Name: Brook

Question: I have an ok diet, it’s not great because I work a lot and often end up eating late or grabbing a take away but I’m worried this might be why I’m shedding a lot of hair at the moment. Can you tell me specifically which vitamin deficiency causes hair loss?

Answer: Hi, Brook. Any dietary issues severe enough to lead to a significant nutritional imbalance can cause hair loss. However, there are a few key vitamins and minerals that are more likely to cause thinning hair that others.

vitamins minerals diet nutrition supplements tablets healthy hair growthA study was published in the Dermatology Practical and Conceptual medical journal in January 2017 detailing precisely which vitamin and mineral deficiencies were most likely to cause hair loss. Their findings were taken from looking at other studies into the subject and collating them. The outcome, as many hair specialists suspected, pinpointed deficiencies in iron, zinc, selenium or vitamin D as the key culprits.

Iron is important for haemoglobin production, which allows oxygen to be efficiently transported around the body. In cases of iron deficiency (anaemia) this process is hindered, causing the body to divert energy towards conserving oxygen and away from non-essential functions, such as the hair growth cycle. As a consequence, hair fall may occur from all over the scalp which tends to take around three months to become noticeable.

Zinc is one of the key minerals involved in hair health due to its role in cell production and regrowth. A lack of zinc can cause the same type of disruption to the hair growth cycle as is seen with iron deficiency anaemia, but – in addition to causing hairloss – it can lead to hair shafts becoming brittle and weak, making them more prone to hair breakage.

Selenium deficiency is rare, except in certain regions of the world including China and Tibet, as it is only required in relatively small amounts which can generally be found in a varied diet. However, as selenium contributes to the maintenance of healthy hair, the normal functioning of our immune system and the protection of cells from oxidative stress – a factor identified as being linked to premature hair loss in men – if there are low levels of this mineral in the body, hair health may suffer as a result. Furthermore, selenium is critical in order to convert the thyroid hormone thyroxine (T4) into triiodothyronine, so if there is a deficiency, hypothyroidism symptoms may present – one of which is hair loss.

Vitamin D’s role in the process of cell division and helping to maintain the normal functioning of the immune system also assists with the maintenance of healthy hair. Various studies have linked ‘the sunshine vitamin’ to improved hair growth in cases from hereditary hair loss to the autoimmune disorder Alopecia Areata. As such, when vitamin D levels are depleted, thinning hair may occur.

Vitamin D3, in particular, was only recently hailed as playing a far more crucial role in hair growth than other forms of the vitamin. This is why vitamin D3 appears, alongside zinc, selenium, biotin and other key vitamins, minerals, amino acids and botanical extracts identified by Belgravia’s hair specialists as being beneficial to hair health, in the Centre’s highly-targeted Hair Vitalics for Men and Hair Vitalics for Women food supplements.

Biotin, whilst not mentioned in the 2017 study, is well established as being important for the maintenance of normal, healthy hair growth. It is a water soluble B vitamin (B7), active in many enzyme systems in the body, that is necessary for the production of normal skin and scalp secretions and ensuring hair and skin health is maintained. As with selenium, biotin deficiency is rare but when present can cause hair loss or thinning hair.

Hair Vitalics for Women and Hair Vitalics for Men healthy hair supplement hair specialist Belgravia CentreThe hair loss condition these deficiencies tend to present as is temporary, generally lasting no more than six months, and is called Telogen Effluvium. In more persistent cases it may last longer and be reclassified as Chronic Telogen Effluvium, but is still considered temporary. The only time when the hair thinning may be permanent is in cases where there is an underlying genetic predisposition to Androgenetic Alopecia (Male Pattern Baldness and Female Pattern Hair Loss) as its onset can be accelerated by these temporary conditions.

When considering nutritional deficiencies it is important not just to review your diet in terms of what you eat and drink. Of course it is vital to ensure you are feeding your body a healthy balance of key vitamins, minerals and fatty acids etc, but it is also beneficial to look at whether there are any other symptoms that could suggest an underlying health issue or undiagnosed illness, meaning your body may not be able to absorb some nutrients properly. For example, the autoimmune disorder Coeliac’s disease – where those affected are intolerant to gluten – can hinder absorption of vitamin B12 and folate, resulting in pernicious anaemia.

There are in fact a number of dietary factors that can influence both hair growth and hair fall. Sugar consumption – which can be unexpectedly high due to the rise in ‘hidden sugars’, particularly in convenience foods – has been linked to thinning hair. As, conversely, have diet drinks and foods. Eating too much red meat is another dietary minefield when it comes to general health concerns as well as hairloss, though those with highly restrictive or elimination diets, such as vegetarians or vegans, also need to be particularly mindful of their nutrition in order to maintain healthy hair growth.

Whilst all these are theoretical possibilities, in general, as long as you eat a well-balanced diet and have a relatively healthy lifestyle, including a decent amount of exercise, these issues should not be too much cause for concern.

Two other pertinent non-nutritional factors which may be worth monitoring are your lifestyle and stress levels. Stress is a well-established cause of hair loss in men and women, and lifestyle issues such as regularly not getting enough sleep, and smoking, all place strain on the body and have been shown to result in unusual levels of shedding.

This is why, when considering what causes hair loss it is rarely as simple as pinpointing one specific vitamin deficiency. It is important for hair specialists to take an holistic view, including looking at a person’s overall wellbeing, given the many factors – besides genetics – that can be involved, in order to correctly diagnose the problem and recommend appropriate hair loss treatments where necessary.


The Belgravia Centre Hair Loss Clinic - Hair Loss Specialist ConsultationThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


Related Stories


Belgravia Centre Hair Loss Treatment Before and After Results - New Success Story

alert male pattern hair loss the belgravia centre 16 07 2018A new entry has just been added to Belgravia’s Male Hair Loss Treatment Success Stories gallery.

Mr S, pictured, is seeing lots of new growth in the areas affected by his hereditary condition.

Find out what he had to say and see his regrowth results close up, or find out more about treating Male Pattern Baldness by clicking the buttons below…

(Results may vary and are not guaranteed)

 

VIEW SUCCESS STORY

TreatmenT information 

 


Belgravia Centre Hair Loss Clinic Hair Loss Specialist Free ConsultationThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


Androgenetic alopecia (AGA), perhaps better known as Male Pattern Baldness, is the most common form of hair loss worldwide. Therefore it may be surprising to learn that there are currently only two treatments appropriately licensed or approved by the UK and USA medical regulatory bodies, the MHRA and the FDA.

These well-established topical and oral medications have been shown to be effective in stabilising shedding, promoting regrowth and, when used on an on-going basis, preventing baldness.

cream lotion solutionNow Cassiopea, a small Italian biotech company, is developing a novel clascoterone antiandrogen treatment which goes by the brand name of Breezula in the hopes of adding to this roster.

Promising trial results so far

The double-blind Phase 2 clinical currently taking place across six different sites in Germany, aims to establish the efficacy and safety of clascoterone, using a placebo vehicle for comparison. Though 404 participants, aged 18-55 years with mild to moderate Male Pattern Baldness, were initially enrolled, there are now 375 subjects with available data suggesting some volunteers may have dropped out.

Results from the half-way, six month point in the trial were announced via press release by Cassiopea on 16th July 2018. They showed clascoterone to have similar results to the clinically-proven drug finasteride 1mg in terms of efficacy.

Finasteride 1mg is a DHT-blocker, inhibiting this hormone which is known to cause thinning hair and hair loss by attaching to hair follicles along the top of the scalp, from crown to vertex, in men with a genetic predisposition to Male Pattern Baldness. It comes in an oral, one-a-day 1mg tablet form which has been clinically-proven. A topical finasteride solution – whilst not yet approved by the necessary medical regulatory bodies – is currently being developed.

Breezula has a similar effect in that it is designed to inhibit DHT through clascoterone being absorbed from where the lotion is applied on the scalp, into the hair follicles and bloodstream, rather than the current system option. Systemic medication, including finasteride 1mg, involves a prescription drug entering the body via the bloodstream and then being circulated to the relevant areas, such as the hair follicles.

The developers say that Breezula also ‘reduces the skin’s production of prostaglandin D2, a hormone-like compound that, in elevated levels, can inhibit hair growth’.

Various doses are being tested, with a 7.5 per cent solution applied twice daily to the scalp currently producing the most positive results with a 62 per cent improvement in hair growth across the trial participants. Interestingly, the men being studied are noted as having genetic hairloss that affects their vertex – top of the scalp – or their temporal regions. This is particularly noteworthy given finasteride has not been proven – as a result of a lack of data – in relation to treating a receding hairline. The range of hair treatments being tested can be seen in the table below. Continues below…

Six Month Interim Analysis Efficacy Results - PP - Clascoterone Breezula - Male Pattern Baldness treatment clinical trial results July 2018

Six Month Interim Analysis Efficacy Results (PP) of Clascoterone (Breezula) topical treatment for Male Pattern Baldness. Information released by Cassiopea, July 2018 [TAHC = Target Area Headcount; HGA = Hair Growth Assessment; BID = twice per day; QD = once per day; Vehicle = Placebo] 

Minimising side effects

Medications that are applied topically tend to have a lower side effect profile than systemic medications. As such, it is no surprise Cassiopea claims that, so far, Breezula has demonstrated minimal side effects.

Those that have occurred have been reported as local skin infections classified as ‘mild’ and not related to any kind of ‘hormonal disturbances’. The company explains this as follows: ‘Clascoterone is metabolized quickly to Cortexolone, a physiological component of the body’s endogenous pool of corticosteroids, thus attaining high local activity without having any systemic effects.’

Former president of the North American Hair Research Society and the International Society of Hair Restoration Surgery, Dr. Ken Washenik, commented on the interim findings: “The interim data on Clascoterone represents a dramatic advance in the treatment of AGA that has been on the ”bucket list” of physicians who treat AGA and their patients for decades. The promise of the same, or improved, efficacy, without any systemic androgen-related side effects, from a topical application, compared to a systemic medication, provides important hope for these patients and their physicians.”

To be tested for women’s hair loss

Trials for the men’s version continue with a view to gaining FDA approval as soon as possible. This is estimated to be around 2022 which isn’t great news for those wanting to address this permanent, progressive form of hair loss sooner rather than later.

The encouraging six month results have led to a women’s trial getting the green light, however. Breezula will be tested in clinical trials as a potential treatment for Female Pattern Hair Loss though the start date is yet to be announced.

Although high strength minoxidil can be used by both sexes, finasteride is neither recommended nor approved for use by women as a hair loss treatment. Therefore, if a clinically-proven, safe and effective antiandrogen for women were to be developed, this would certainly be considered a significant breakthrough and a welcome addition to current hair loss treatment options.


Hair Vitalics for Men food supplement healthy hair growthThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


Related Stories


Belgravia Centre Hair Loss Treatment Before and After Results - New Success Story

Aalert female pattern hair loss and hair breakage the belgravia centre 12 07 2018 new entry has just been added to Belgravia’s Female Pattern Hair Loss and Hair Breakage Treatment Success Stories galleries.

Mrs F, pictured, is happy with the way her hair is improving since she started using treatment.

Find out what she had to say and see her regrowth results close up, or find out more about the treatment of  Female Pattern Hair LossTraction Alopecia and Hair Breakage by clicking the buttons below…

(Results may vary and are not guaranteed)

 

VIEW SUCCESS STORY

FEMALE PATTERN HAIR LOSS TREATMENT

HAIR breakagE 

 


The Belgravia Centre Hair Loss ClinicThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.