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P-3074 Topical Finasteride Male Pattern Hair Loss Treatment Trial

A global trial that will look into a new application method for one of the most commonly-used hair loss drugs is now recruiting volunteers to take part.

The study been announced by Swiss pharmaceutical company Polichem, and the randomised, double-blind Phase 3 trial is hoping to enlist an impressive 450 volunteers who will be involved over a six-month period.

Finasteride 1mg Aindeem tabletsTopical finasteride

The trial is certainly of interest to the medical community as Polichem has announced that it will be using a topical version of the drug finasteride, one of just two MHRA and FDA approved drugs for the treatment of Male Pattern Hair Loss. Normally, this drug is taken orally.

At more than 60 sites across Belgium, Germany, Spain, Russia and Hungary, the Polichem trial will explore the clinical efficacy and safety of what has been named P-3074. The company further describes this as a cutaneous spray solution.

Participants must all be aged between 18 and 40, and they must be displaying moderate to advanced hair thinning that registers as type III vertex, IV or V on the Norwood Hamilton scale. They must also be willing to have a tiny tattoo on their scalp, so that testers can easily return to the same area on their scalp during the study.

In an earlier Polichem trial involving 60 men with androgenetic alopecia, Essex-based testers employed by the company announced that Ultraviolet light would be used during treatment, apparently to cause a reaction that would make the drug more effective. There is no specific mention of UV light being used this time around.

The finasteride used in the trial will be a 0.25 per cent solution, and a percentage of the volunteers will be given the more traditional oral version of finasteride in usual 1mg doses so that results can be compared.

There are a long list of reasons why people may be excluded from this particular trial, including abnormal scalp findings, hair transplant surgery and a history of infertility. Use of any of a large number of drugs would render an applicant unsuitable, too, including finasteride and also minoxidil – the other MHRA and FDA approved Male Hair Loss Treatment. The study is slated for completion by the end of 2017.

Tailored treatment plan

At Belgravia, men with hereditary hair loss are first assessed then diagnosed by a specialist who then provides them with a comprehensive list of options tailored to their medical requirements, level and pattern of shedding. Typically they will recommend a combination approach which includes both oral finasteride 1mg and minoxidil to be applied directly to the scalp and specifically chosen from a number of high strength minoxidil products available from Belgravia’s in-clinic pharmacies.

Alongside these key medications, a tailored treatment plan can include a number of other elements to help maximise regrowth. Hair Growth Boosters such as Hair Vitalics, a food supplement for healthy hair growth which contains a proprietary blend of essential vitamins, minerals, amino acids and botanicals is formulated to help nourish the scalp. The HairMax LaserComb, meanwhile, uses low level laser light energy to penetrate soft tissue on the scalp and can encourage hair growth. A choice of these boosters can often be included free of charge to Belgravia clients when a full annual hair loss treatment course is purchased.

Additionally, the support that men receive throughout their treatment course from trained professionals is frequently mentioned as being an enormous relief, as well as motivational.

While the Polichem trial is certainly interesting, for men worried about a thinning crown or receding hairline, there are already proven hair loss solutions that can help to both stop hair falling out and also encourage new growth. The best place to start is with a professional consultation.


The Belgravia Centre Hair Loss ClinicThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


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