WE CAN HELP
Book a FREE consultation  
For a free consultation or assistance, please call 020 7730 6666

Browse by Category

Can Propecia / Finasteride Increase Chances of Developing Breast Cancer?

In December 2009 the Medicines and Healthcare Product Regulatory Agency (MHRA) published a  public assessment report following individual case reports that suggested the possibility of an association between finasteride and male breast cancer.

Propecia FoilImportant information for Propecia users: No cases of male breast cancer associated with Propecia (finasteride 1 mg) have been reported in the UK to date, nor were any cases of breast cancer recorded in the 5 year Propecia clinical trials that consisted of 4,000 men. Most of the findings in this report relate to Proscar which is a dose of finasteride five times that of Propecia (5 mg), used for the treatment of benign prostatic hyperplasia.

Why was the report carried out?

Although the overall incidence of male breast cancer in clinical trials in patients who received 5mg finasteride (Proscar) was not significantly different compared to patients on a placebo, the data from the trials showed there was a trend towards male breast cancer occurring more frequently in patients who had received finasteride than in those who did not.

How significant was the increased rate of breast cancer for the active product compared to the placebo?

5mg finasteride = 7.8 cases per 100,000 patient years*

placebo = 3.8 cases per 100,000 patient years*

*patient years = the number of patients in a study multiplied by the number of years these patients were followed.

So to put this more clearly; if this were a 5 year study, and therefore 20,000 people took part, out of those 20,000, 1.56 people who used finasteride 5 mg would have contracted male breast cancer whereas 0.76 would have contracted breast cancer with the placebo (that’s about 3 in 40,000 vs. about 3 in 80,000).

Outcome

The report concluded that the following statement should be added to the information leaflet provided with Propecia (hair loss treatment) and Proscar (Benign Prostatic Hyperplasia treatment) information leaflets:

Possible side effects
You should promptly report to your doctor any changes in your breast tissue such as lumps, pain or nipple discharge as these may be signs of a serious condition, such as breast cancer.

To Summarise

Out of the tens and perhaps hundreds of thousands of men that have used finasteride 1 mg (Propecia) in the UK, not one case of associated breast cancer has been reported to date. Worldwide three cases have been reported.

Share this article

No Comments

No comments yet.

Comment on this article

* required field

Will not be published

Online Consultation

Submit an instant online consultation so that one of Belgravia’s hair loss specialists can diagnose your condition and recommend an effective course of treatment, wherever you live.

26 Mar

‘Argan Oil Hair Loss Treatment is Not Working’

Name: Nilesh Question: I am using argan oil hair loss treatment but it is not working. My hair is thinner than before. I apply every night and every day but still my hair loss. What can I do? Answer: Hi, Nilesh. Argan oil is one of a number of natural products that people believe can treat hair loss but, sadly, this is untrue. […]

Read full article »
25 Mar

Biocellular Regenerative Alopecia Therapy Trial is Recruiting

Two novel treatment possibilities for Alopecia Areata – the autoimmune disorder that causes patchy hair loss – are to be combined for a new clinical trial, which is now recruiting participants. Announced by US-based stem cell specialists Regeneris Medical, the trial is broadly similar to one announced last year by another company and in which […]

Read full article »
24 Mar

Success Story Alert! New Male Hair Loss Treatment Entry

A new entry has just been added to Belgravia’s Male Hair Loss Treatment Success Stories gallery. After six months, this patient has seen improvement to the general density of his hair and is happy with the progress. Find out what this client had to say and see his regrowth results close up, or find out more […]

Read full article »