WE CAN HELP
Book a FREE consultation  
For a free consultation or assistance, please call 020 7730 6666

Browse by Category

Are Fathers To Blame For Passing On Genetic Hair Loss?

The myth that hair loss is passed on solely from the female side of a family was busted a long time ago. However, new research appears to question the previously held belief that genetic hair loss could be passed on by either parent. A widely-reported study published in the Nature Genetics journal suggests that many traits are actually more likely to be inherited from our fathers – potentially including hair loss.

New Research Finds Fathers May Pass On Hair Loss GeneImprinted genes

Scientists found that, although we inherit a similar amount of DNA from each of our parents, we tend to actively ‘use’ more that we inherit from our dads. This American study is the first of its kind to find that mammals are more genetically similar to their fathers than mothers.This breakthrough will allow advanced studies into the development of diseases and conditions brought about by these genetic mutations, including cancer and diabetes, as well as androgenetic alopecia (more commonly known as male pattern baldness or female hair loss) which previous studies have concluded is likely to be brought about by a parentally-imprinted gene.

Professor Fernando Pardo-Manuel de Villena, from University of North Carolina School of Medicine, explained: “This is an exceptional new research finding that opens the door to an entirely new area of exploration in human genetics”.

We know there are 95 genes that are subject to this parent-of-origin effect. They’re called imprinted genes, and they can play roles in diseases, depending on whether the genetic mutation came from the father or the mother. Now we’ve found that in addition to them, there are thousands of other genes that have a novel parent-of-origin effect.”

Study methods

The research was carried out on mice which were specially bred for the study; three different species of mice with different genes who were all descended from a sub-species of mice that evolved on different continents were selected initially. These mice were then bred in captivity to create nine different types of offspring which were then used to produce another generation of mice.

This Latest DNA Research Was Carried Out On MiceOnce these mice became adults, researchers examined them, looking at the expression of genes in four different kinds of tissue, employing RNA sequencing technology to identify gene expression in the brain. The research team then determined where every single piece of each mouse’s genetic information in their DNA had been inherited from – their mother or their father.

Research findings

The study findings showed an imbalance, rendering the test mice’s brain genes significantly more like their father’s, meaning an increased uptake of paternal genetic mutations. From this the scientists were able to conclude that genes may have different consequences depending on who they are inherited from.

Professor de Villena noted: “This expression level is dependent on the mother or the father. We now know that mammals express more genetic variance from the father. So imagine that a certain kind of mutation is bad. If inherited from the mother, the gene wouldn’t be expressed as much as it would be if it were inherited from the father. So, the same bad mutation would have different consequences in disease if it were inherited from the mother or from the father.”

This new information could be used to further many health causes, including giving us a better understanding of some hair loss conditions and, through further testing, perhaps identifying new ways in which we can prevent or treat them in the future.

For now though, if you start to notice signs of hair loss it is best to contact a specialist who will be able to diagnose your condition and discuss the most effective hair loss treatments for your specific needs, with you.


Belgravia Centre Hair Loss ClinicThe Belgravia Centre

The Belgravia Centre is the leader in hair loss treatment in the UK, with two clinics based in Central London. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation Form from anywhere in the UK or the rest of the world. View our Hair Loss Success Stories, which are the largest collection of such success stories in the world and demonstrate the levels of success that so many of Belgravia’s patients achieve. You can also phone 020 7730 6666 any time for our hair loss helpline or to arrange a free consultation.


Related Stories


Share this article

No Comments

No comments yet.

Comment on this article

* required field

Will not be published

Online Consultation

Submit an instant online consultation so that one of Belgravia’s hair loss specialists can diagnose your condition and recommend an effective course of treatment, wherever you live.

08 Dec

Success Story Alert! New Male Hair Loss Treatment Entry

A new entry has just been added to Belgravia’s Male Hair Loss Treatment Success Stories gallery. Jim, pictured, has maintained an increased hair density since he started his bespoke Belgravia course. Find out what he had to say and see his regrowth results close up, or find out more about treating Male Pattern Baldness by clicking the buttons […]

Read full article »
08 Dec

Hair Loss Can Make Men Look Up to Eight Years Older Than They Are

A new survey has revealed that when it comes to physical factors that influence how old you appear, hair loss is the most ageing. Thinning hair tops ageing factors According to the findings, being overweight or having a moustache added an average of two years to a man’s perceived age. Yet, although greying hair added seven years, obvious Male […]

Read full article »
07 Dec

Success Story Alert! New Male Hair Loss Treatment Entry

A new entry has just been added to Belgravia’s Male Hair Loss Treatment Success Stories gallery. This patient is happy with his regrowth in general; his photoscans show visible improvements on both top and crown areas. Find out what he had to say and see his regrowth results close up, or find out more about treating Male Pattern […]

Read full article »